Product Details
| Product Name: Mutated EGFR-IN-1 | CAS No.: 1421372-66-8 |
| Min. Order: 1KG | Purity: 98% |
| Supply Ability: g-kg-tons, free sample is available | Release date: 2025/09/25 |
| Lead time: In stock, ready for shipment | Packaging: bag/bottle/drum/IBC |
| Delivery: By express, by air, by sea | Delivery: Manufacturer, advantage product |
| COA, MSDS: Manufacturer, advantage product | Name: Tina |
1. Materials information
| Name | N1-(2-(dimethylamino)ethyl)-5-methoxy-N1-methyl-N4-(4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl)benzene-1,2,4-triamine |
|---|---|
| Synonym | More Synonyms |
| Description | Mutated EGFR-IN-1 is a useful intermediate for the inhibitors design for mutated EGFR, such as L858R EGFR, Exonl9 deletion activating mutant and T790M resistance mutant.IC50 value:Target: Mutated EGFR inhibitorMore information can be found in Patent WO 2013014448 A1.2 - (2, 4, 5 - substituted -anilino) pyrimidine derivatives as egfr modulators useful for treating cancer. |
|---|---|
| Related Catalog | Research Areas >> Cancer |
| Target | EGFRL858R EGFRExon 19 deletion/T790M EGFRT790M |
| References | [1]. Patent WO 2013014448 A1. 2 - (2, 4, 5 - substituted -anilino) pyrimidine derivatives as egfr modulators useful for treating cancer. |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 676.5±65.0 °C at 760 mmHg |
| Molecular Formula | C25H31N7O |
| Molecular Weight | 445.560 |
| Flash Point | 363.0±34.3 °C |
| Exact Mass | 445.259003 |
| PSA | 84.47000 |
| LogP | 2.17 |
| Vapour Pressure | 0.0±2.1 mmHg at 25°C |
| Index of Refraction | 1.635 |
| Storage condition | 2-8℃ |
| Mutated EGFR-IN-1 |
| AZD9291 intermediate 3 |
| 1,2,4-Benzenetriamine, N-[2-(dimethylamino)ethyl]-5-methoxy-N-methyl-N-[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]- |
| N-[2-(Dimethylamino)ethyl]-5-methoxy-N-methyl-N-[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]-1,2,4-benzenetriamine |
| N1-[2-(diMethylaMino)ethyl]-5-Methoxy-N 1-Methyl-N4-[4-(1-Methyl-1H-indol-3-yl)-2-pyriMidinyl]benzene-1,2,4-triamine |
2. Packaging of materials
For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.
For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product.
Or smaller package 1kg/bottle, 10kgs/bottle as request.
3. Shipping & Delivery
By Express
Provide door to door service
Suitable for goods under 50kg
Delivery: 3-7 days
Cost: low cost
By Air
Provide airport to airport service
Suitable for goods over 50kg
Delivery: 3-14 days
Cost: high cost
By Sea
Provide seaport to seaport service
Suitable for goods over 100kg
Delivery: 2-45 days
Cost: low cost
4. Contact information
For more details, pls contact us freely.
Email address: Tina@fdachem.com
Mob: 86 13213167925
WhatsApp/Skype/Wechat/LINE: 86 13213167925
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