Product Details
| Product Name:
(+)-SHIN1 |
CAS No.:
2443966-90-1 |
| Supply Ability:
10g |
Release date:
2025/07/19 |
Product Introduction
Bioactivity
| Name | (+)-SHIN1 |
| Description | (+)-SHIN1 ((+)-RZ-2994) is the active (+) enantiomer of SHIN1, which inhibits human serine hydroxymethyltransferase 1 and 2 (SHMT1/2). |
| In vitro | (+)-SHIN1 ((+)-RZ-2994) exhibits potent inhibition of cytosolic SHMT1, with IC50 values of less than 50 nM in SHMT2 deletion cells and 870 nM in HCT-116 cells, effectively blocking cell growth [1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 100 mg/mL (249.71 mM), Sonication is recommended.
|
| Keywords | (+)SHIN1 | SHIN1 | RZ-2994 | (+) SHIN1 | RZ2994 | RZ 2994 | SHIN 1 | (+)-SHIN-1 | SHIN-1 |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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