Product Details
| Product Name:
Pipobroman |
CAS No.:
54-91-1 |
| Min. Order:
1KG |
Purity:
95%~99.99% |
| Supply Ability:
10 MT/ Month |
Release date:
2024/10/22 |
Heidi 297
| Pipobroman Basic information |
| Product Name: |
Pipobroman |
| Synonyms: |
1,1'-(Piperazine-1,4-diyl)bis(3-bromopropan-1-one);Pipobroman;1,4-Bis(3-bromo-1-oxopropyl)piperadine;A-8103;Amedel;NSC-25154;Vercyte;3-bromo-1-[4-(3-bromopropanoyl)piperazin-1-yl]propan-1-one |
| CAS: |
54-91-1 |
| MF: |
C10H16Br2N2O2 |
| MW: |
356.056 |
| EINECS: |
|
| Product Categories: |
HYDROMOX |
| Mol File: |
54-91-1.mol |
 |
| |
| Pipobroman Chemical Properties |
| Melting point |
106-107℃ |
| Boiling point |
487℃ |
| density |
1.691 |
| refractive index |
1.6220 (estimate) |
| Fp |
248℃ |
| pka |
-0.56±0.70(Predicted) |
| color |
Crystals from H2O |
| EPA Substance Registry System |
Pipobroman (54-91-1) |
| Toxicity |
LD50 orl-rat: 220 mg/kg IYKEDH 4,467,73 |
| |
| Pipobroman Usage And Synthesis |
| Originator |
Vercyte ,Abbott ,US ,1966 |
| Uses |
diuretic, antihypertensive |
| Manufacturing Process |
To a solution of 17.2 g (0.10 mol) of 3-bromopropionyl chloride in 100 ml of anhydrous benzene was added dropwise with stirring a solution of 8.6 g (0.10 mol) of anhydrous piperazine in 20 ml of dry chloroform over a period of 30 minutes. The temperature rose spontaneously to 45°C during the addition. After the temperature ceased to rise, stirring was continued for another hour. The reaction mixture was then filtered to remove the piperazine hydrochloride by-product. The filtrate was evaporated to dryness and the residue recrystallized from ethanol to obtain the desired N,N'-bis-(3bromopropionyl)piperazine as a white crystalline solid melting at 103°C to 104°C. The identity of the product was further established by elemental analysis. |
| Brand name |
Vercyte (Abbott). |
| Therapeutic Function |
Antineoplastic |
| Safety Profile |
Poison by ingestion,subcutaneous and intraperitoneal routes. An experimentalteratogen. Other experimental reproductive effects.Human mutation data reported. When heated todecomposition it emits very toxic fumes of Br- and NOx. |
| |
| Pipobroman Preparation Products And Raw materials |
| Raw materials |
Piperazine-->3-Bromopropionyl chloride |
Company Profile Introduction
Technology research and transfer of pilot screening, pilot scale-up and mass production solutions , for pharmaceutical intermediates, biologicals and fine chemicals (Not including inflammable , explosive , hazardous goods ) ; Market : Nano material , metal catalyst , raw material of cosmetics , pharmaceutical intermediates , chemicals , photoelectric material , import and export of technology and goods (For projects subject to approval according to law, business activities can be carried out only after approval by relevant departments ).
Recommended supplier
| Product name |
Price |
|
Suppliers |
Update time |
|
|
$48.00/100mg |
VIP6Y
|
TargetMol Chemicals Inc.
|
2025-11-04 |
China