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Postion:Product Catalog >Pharmaceutical intermediates>Heterocyclic compound>Pyridine compound>Pyridine derivatives>N-Boc-3-pyrrolidinone
N-Boc-3-pyrrolidinone
  • N-Boc-3-pyrrolidinone
  • N-Boc-3-pyrrolidinone
  • N-Boc-3-pyrrolidinone
  • N-Boc-3-pyrrolidinone
  • N-Boc-3-pyrrolidinone

N-Boc-3-pyrrolidinone NEW

Price $15 $13
Package 1kg 500kg
Min. Order: 1kg
Supply Ability: 50000tons
Update Time: 2024-04-07

Product Details

Product Name: N-Boc-3-pyrrolidinone CAS No.: 101385-93-7
Min. Order: 1kg Purity: 99.99%
Supply Ability: 50000tons Release date: 2024/04/07

Chinese name: 1-tert-butoxy-3-pyrrolidone

English name :N-Boc-3-pyrrolidinone

CAS:101385-93-7

Molecular formula C9H15NO3

MDL number :MFCD01631194

Molecular weight :185.22

category

Pharmaceutical intermediates: pyridine derivatives

Melting point :34-38 °C(lit.)

Boiling point :270.9±33.0 °C(Predicted)

Density :1.133± 0.06g /cm3(Predicted)

Flash point :>230 °F

Storage conditions :Store at 0-5°C

Solubility: Soluble in methylene chloride, ethyl acetate, methanol

Acidity coefficient (pKa):-1.79±0.20(Predicted)

Form: low melting point solid

Color: White to yellow to orange

water solubility :Insoluble in water.

InChIKey:JSOMVCDXPUXKIC-UHFFFAOYSA-N

use

1-tert-butoxy-3-pyrrolidone is a starting material and a useful intermediate for organic synthesis.

Synthesis method

In a dry 500 ml reaction flask, the Dess Martin oxidizer (45.9 g, 108 mmol) was slowly added in 3 batches to a methylene chloride solution (300 m L) of 3-hydroxypyrrolidine-1-carboxylate (10 g, 54 mmol). The resulting reaction mixture was stirred at room temperature for 16 h. At the end of the reaction, the reaction mixture was filtered through diatomite with ethyl acetate as eluent to remove the insoluble solid, and the filtrate was removed under vacuum. The residue was separated and purified by silica gel column chromatography and eluted with 0-8% ethyl acetate/n-hexane gradient to obtain the target product 1-tert-butoxy-3-pyrrolidone (9.8g, 97%).


Company Profile Introduction

-WUHAN BOYUAN IMPORT & EXPORT CO.,LTD.. is specialized in R&D, manufacturing and marketing APIS, Food Additives,Inorganic Chemicals,Organic Intermediate,Health Care Products,Feed Additives,Chemical Reagents,Daily Chemicals etc.More than 70 percent products are exported to Europe, America, Japan and Southeast Asia. In the past years, WUHAN BOYUAN IMPORT & EXPORT CO.,LTD. has established its professional team and advanced managements, excels in product sourcing and customized products. WUHAN BOYUAN IMPORT & EXPORT CO.,LTD. has built close collaborations with several well-known institutes in China. Development of new fine chemical, custom synthesis has been a significant part of our chemical's production. The essence of our business is commitment to customer service by meeting and/or exceeding our client's expectations of cost, quality, and efficient service. We are confident that our competitive edge will provide the foundation ensure for our customers to be successful in their own market areas. Our company offers variety of products which can meet your multifarious demands. We adhere to the management principles of "quality first, customer first and credit-based" since the establishment of the company and always do our best to satisfy potential needs of our customers. Our company is sincerely willing to cooperate with enterprises from all over the world in order to realize a win-win situation since the trend of economic globalization has developed with anirresistible force

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  • Since: 2014-04-18
  • Address: Hong Kong
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