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Postion:Product Catalog >Biochemical Engineering>Polypeptide>Bivalirudin Thrombin Inhibitor
Bivalirudin Thrombin Inhibitor
  • Bivalirudin Thrombin Inhibitor
  • Bivalirudin Thrombin Inhibitor
  • Bivalirudin Thrombin Inhibitor
  • Bivalirudin Thrombin Inhibitor
  • Bivalirudin Thrombin Inhibitor

Bivalirudin Thrombin Inhibitor

Price Get Latest Price
Package 25Kg/Bag
Min. Order: 2Kg/Bag
Supply Ability: 20 tons
Update Time: 2024-04-22

Product Details

Product Name: Bivalirudin Thrombin Inhibitor CAS No.: 128270-60-0
Min. Order: 2Kg/Bag Purity: 99% up
Supply Ability: 20 tons Release date: 2024/04/22

Product Information

Product name

Bivalirudin Acetate

CAS No.

128270-60-0

Synonyms

BIVALIRUDIN;BIVALIRUDIN TRIFLUOROACETATE;Bivalirudin, TFA;BITTERMELONP.E;Human Bivalirudin;Bivalirudin Acetate;H-D-Phe-Pro-Arg-Pro-Gly-Gly-Gly-Gly-Asn-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr-Leu-OH;H-D-Phe-Pro-Arg-Pro-Gly-Gly-Gly-Gly-Asn-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr-Leu-OH trifluoroacetate salt

Molecular Formula

C98H138N24O33

Molecular Weight

2180.29

Quality Standard

98% up by HPLC, USP, cGMP, DMF

Appearance

white to off-white crystalline powder

Usage

Function of Bivalirudin

Bivalirudin is a synthetic anticoagulant. It is an analog of naturally occurring hirudin. It is a polypeptide composed of 20 amino acids. It can bind to thrombin with high affinity and specifically inhibit the activity of thrombin. The reaction catalyzed and induced by thrombin. Bivalirudin can not only bind to free thrombin in plasma, but also bind to thrombin linked to blood clots. This binding is reversible and does not require the presence of ATⅢ. Bivalirudin has a strong anticoagulant effect, and has antithrombotic effect on a variety of animal arterial and venous models. Bivalirudin can prolong partial thromboplastin time (APTT), thrombin time (PT) and activated clotting time (ACT).


Bivalirudin is suitable for patients with unstable angina and unstable angina pectoris undergoing PTCA; percutaneous intervention in acute ischemic coronary complications.


COA of Bivalirudin

  Items

Specifications

Results

Appearance

White or almost white crystalline powder

White powder

Assay (by HPLC)

98%-102%

99.34%

Identification

Positive

Positive

Absorbance(E1cm)

465-495

482.5

Melting point

191C - 195C

93.5C-195C

Loss on drying

< 0.5%

0.19%

Specific rotation

+288-298

290.2

Residue on ignition

< 0.10%

0.03%

Related substances

Total related substances < 1.5%

< 1.3%

Single related substances < 0.5%

< 0.4%

Residue solvents

< 0.2%

0.10%

Heavy metals

< 20 ppm

< 10 ppm

Conclusion

Meet the specification of enterprise standard

Company Information

Article illustration



Company Profile Introduction

Sinoway Industrial co., ltd. was established in 1987 in Xiamen, China, and now has been a leading group specialized in research, development, custom manufacturing and trading of pharmaceutical intermediates, APIs, health and food supplements, cosmetic raw materials, herbal extracts, polypeptides and prostaglandin derivatives, etc.. We have passed ISO9001:2015. With qualified products, competitive price and excellent service, we have received great reputation of our customers from all over the world, including Southeast Asia, Europe, North America, South America, Middle East and other countries. We have over 20 years good partners in Japan、Korea and Switzerland. Sinoway has a professional R&D team. We have built close cooperative relationships with many research institutes and universities in China. Moreover, Sinoway combines market analysis with technology, providing new business trends to our clients. In addition, we have very close cooperation relationships with many Chinese pharmaceutical factories. These pharmaceutical manufacturers have GMP regulated workshops, advanced production and testing equipments, first-class QC labs and a production team with rich experience. We can supply various Active Pharmaceutical Ingredients and finished products which meet EP/USP/BP standards. Chinese GMP, EU-GMP, COS/CEP certificates with DMF documents are available, and many products have been approved by FDA. We believe that quality and innovation are vital for an enterprise. Adhering to the business philosophy of integrity and win-win cooperation, Sinoway is looking forward to have a bright future with you together.

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  • Since: 1996-07-16
  • Address: Fujian China ,16F, Huicheng Comm. Complex, 839 Xiahe RD.
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