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Postion:Product Catalog >2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)acetamide
2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)acetamide
  • 2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)acetamide

2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)acetamide

Price $1 $1 $1
Package 1kg 25kg 100kg
Min. Order: 1kg
Supply Ability: 1000kg
Update Time: 2025-11-25

Product Details

Product Name: 2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)acetamide CAS No.: 1083326-46-8
Min. Order: 1kg Purity: 98%
Supply Ability: 1000kg Release date: 2025/11/25

2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)acetamide Basic information
Product Name:2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)acetamide
Synonyms:2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)acetamide;4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-acetamide;2-[4-(tetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]acetaMide;1H-Pyrazole-1-acetaMide, 4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-;(1-(2-AMINO-2-OXOETHYL)-1H-PYRAZOL-4-YL)BORONIC ACID PINACOL ESTER;2-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazol-1-yl]acetamide;2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)acetamide 95%;1-(2-Amino-2-oxoethyl)-1H-pyrazole-4-boronic Acid Pinacol Ester
CAS:1083326-46-8
MF:C11H18BN3O3
MW:251.09
EINECS:
Product Categories:
Mol File:1083326-46-8.mol
Article illustration

2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)acetamide Chemical Properties
Boiling point 440.8±25.0 °C(Predicted)
density 1.21±0.1 g/cm3(Predicted)
storage temp. 2-8°C
pka15?+-.0.40(Predicted)
AppearanceWhite to light yellow Solid

Safety Information
HS Code 2933199090
MSDS Information

2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)acetamide Usage And Synthesis
Uses4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-acetamide, can be used in the preparation of pharmaceutical and biologically active compounds, including inhibitors and therapeutic agents.
Synthesis
Article illustration

269410-08-4

Article illustration

683-57-8

Article illustration

1083326-46-8

Step 1: 4-Pyrazoleboronic acid pinacol ester (200 mg, 1.03 mmol), 2-bromoacetamide (213 mg, 1.54 mmol) and cesium carbonate (1.27 g, 3.92 mmol) were dissolved in acetonitrile (5.0 mL), and the reaction was stirred for 3 hours at 90°C. After the reaction was completed, it was cooled to room temperature, the reaction mixture was diluted with water and extracted twice with ethyl acetate. The organic layers were combined, dried with anhydrous sodium sulfate, filtered and concentrated in vacuum to afford pinacol ester of 1-acetamido-4-boronic acid (174 mg, 67% yield) as a white solid, which could be used in the next reaction without further purification.1H-NMR (400 MHz, CDCl3): δ 7.89 (s, 1H), 7.76 (s, 1H), 6.21 and 5.41 ( brs, 2H), 4.83 (s, 2H), 1.32 (s, 12H).

References[1] Patent: WO2015/156601, 2015, A1. Location in patent: Page/Page column 51; 52
[2] Patent: WO2010/75270, 2010, A1. Location in patent: Page/Page column 170
[3] Patent: WO2015/95128, 2015, A1. Location in patent: Paragraph 0222; 0223
[4] Patent: EP3042907, 2016, A1. Location in patent: Paragraph 0286; 0287
[5] Patent: WO2008/154241, 2008, A1. Location in patent: Page/Page column 160

Company Profile Introduction

Founded in 2014, Henan Aochuang Chemical Co., Ltd. is committed to the development of medical science and material chemistry technology. Based on the advanced technology for chemical and medical , it specializes in the research, development, and sales of pharmaceutical intermediates, electronic intermediates ,battery material intermediates, and other fine chemicals. The company has professionals who have been engaged in chemical production and sales for many years. It is a vigorous pharmaceutical chemical technology enterprise with professional background. 90% of the company's products are sold to Japan, South Korea, Europe and the United States. We have maintained good cooperative relations with many international well-known enterprises, and have been well received by all parties. ? Adhering to the principle of "quality first, customer first, integrity-based, mutual benefit", the company provides customers with high-quality products ranging from grams to tons, and comprehensive services from products to technology, and is willing to work together with all walks of life. , and jointly contribute to the development of the material and pharmaceutical industry!

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