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Postion:Product Catalog >Pharmaceutical intermediates>Heterocyclic compound>Pyridine compound>Methylpyridine>2-Picoline
2-Picoline
  • 2-Picoline
  • 2-Picoline
  • 2-Picoline
  • 2-Picoline
  • 2-Picoline

2-Picoline NEW

Price Get Latest Price
Package 25KG
Min. Order: 1KG
Supply Ability: 50000KG/month
Update Time: 2023-08-29

Product Details

Product Name: 2-Picoline CAS No.: 109-06-8
EC-No.: 203-643-7 Min. Order: 1KG
Purity: 99% Supply Ability: 50000KG/month
Release date: 2023/08/29

CAS:109-06-8
MF:C6H7N
MW:93.13
EINECS:203-643-7
Product Categories:bc0001
Mol File:109-06-8.mol
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2-Picoline Chemical Properties
Melting point -70 °C (lit.)
Boiling point 128-129 °C (lit.)
density 0.942-0.946 at 20 °C 0.943 g/mL at 25 °C (lit.)
vapor density 3.2 (vs air)
vapor pressure 10 mm Hg ( 24.4 °C)
refractive index n20/D 1.500(lit.)
Fp 79 °F
storage temp. Store below +30°C.
solubility H2O: freely soluble
pka5.97(at 20℃)
form Liquid
color Clear pale yellow
PH8.5 (100g/l, H2O, 20℃)
OdorUnpleasant
Odor Typesweaty
explosive limit1.4-8.6%(V)
Water Solubility MISCIBLE
Sensitive Hygroscopic
Merck 14,7400
BRN 104581
Stability:Stable. Flammable. Incompatible with strong oxidizing agents, sulfuric acid, acids, metals, iron (II) sulfate, hydrogen peroxide. Hygroscopic.
InChIKeyBSKHPKMHTQYZBB-UHFFFAOYSA-N
LogP1.11 at 20℃
CAS DataBase Reference109-06-8(CAS DataBase Reference)
NIST Chemistry ReferencePyridine, 2-methyl-(109-06-8)
EPA Substance Registry System2-Methylpyridine (109-06-8)

2-Picoline Usage And Synthesis
Chemical Propertiescolourless to yellow liquid with an unpleasant smell
Chemical PropertiesPicolines are colorless liquids. Strong, unpleasant, pyridine-like odor.“Picoline” is often used as mixed isomers.
Chemical Properties2-Methylpyridine is highly stable in aqueous solutions but decomposes when heated to emit NOx. The chemical also may react with oxidizing agents.
Occurrence2-Methylpyridine is released in atmospheric emissions from coal during processing into tar, pitch and coke (Windholz et al 1983; Naizer and Mashek 1974). It is also a byproduct of coal gasification and liquefaction processes (Pellizzori et al 1979; Stuermer et al 1982) and oil shale retorting (Pellizzari et al 1979). It is present in coal and is released in stack emissions (Opresko 1982). 2-Methylpyridine has been identified in effluences from the following industries: timber products, organic chemicals, pharmaceuticals and public waste treatment facilities (Schackleford and Cline 1983). 2-Methylpyridine also is a constituent of tobacco smoke (Brunneman 1978).
2-Methylpyridine is biodegradable. A 1 mM solution of 2-methylpyridine exposed in soil microorganism was completely degraded in 14-33 d under aerobic conditions, but not degraded after 97 d in anaerobic conditions (Naik et al 1972).
UsesSolvent; intermediate in the dye and resins industries.
Uses2-Picoline is used as an intermediate in agrochemicals and pharmaceuticals. It serves as a solvent as well as to prepare dyes and resins. It finds application as a constituent in cigarette smoke, bone oil, coal tar and coke oven emissions. Further, it acts as a precursor of 2-vinylpyridine, picolinic acid and nitrapyrin. It is also employed to study the electron and proton transfer reactions of lumiflavin. In addition, it is used in the synthetic pathway for the preparation of dearomatized, allylated and carbon-hydrogen bond activated pyridine derivatives.
Uses2-Picoline is used as a reagent in the synthesis of 2-Picolineborane, a non-toxic alternative to sodium borohydride for the labelling of oligosaccharides.
DefinitionChEBI: 2-methylpyridine is a methylpyridine carrying a methyl substituent at position 2.
Production Methods2-Methylpyridine is synthesized by distillation of coal tar or bone oil or by vapor phase reaction of acetaldehyde and ammonia in a 3:1 ratio followed by isolation of 2-methylpyridine from the reaction mixture (Considine 1974). It also can be synthesized from cyclohexylamine with excess ammonia and ZnCl2 at 350°C, resulting in a 40-50% yield; or prepared from ethylene-mercuric acetate adduct with ammonia water with a 70% yield (Windholz et al 1983). Production in 1977 probably exceeded one million pounds (Opresko 1982).

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Packing &shipping&Payment

Packing:25kg/drum
Shipping:by sea or by air
Payment:T/T,western union,moneygram
Packaging Details drum
Port:Tianjin
Lead Time :
Quantity(Kilograms)1 - 10000>10000
Est. Time(days)5To be negotiated

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Article illustrationCompany information
Hebei Mojin Biotechnology Co., Ltd, Our company is a professional in 4'-Methylacetophenone,Levamisole hydrochloride ,N-Methylformamide and other chemical reagents research and development production enterprises. Our business covers more than 30 countries, most of the big customers come from Europe, America and other countries in the world, we can guarantee the quality and price. In recent decades, with the efforts of all employees, we have established many cooperative companies in shandong, henan, guangdong and other places. Our corporate purpose is based on the market, enhance the strength, take the road of scientific and environmental sustainable development, relying on the country. Technology r & d center, increase the investment in r & d, based on the domestic market, expand the international market, manufacturing quality products, sincere service to the society, into a modern, ecological, scientific and technological enterprise world.

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  • Address: Building A, Enjoy city, Zhongshan East Road, Shijiazhuang city, Hebei province
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