3-Bromo-5-fluoro-2-methoxypyrdine Cas 884494-81-9 | China | Manufacturer

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Package	1kg	25kg

Product Details

Product Name: 3-Bromo-5-fluoro-2-methoxypyrdine	CAS No.: 884494-81-9
Min. Order: 1kg	Purity: 98%
Supply Ability: 100kg	Release date: 2025/12/01

3-Bromo-5-fluoro-2-methoxypyridine (corrected from "pyrdine") is a substituted pyridine derivative with the following structure:

Core: Pyridine ring (a 6-membered aromatic ring with one nitrogen atom).
Substituents:
Bromine (Br) at position 3 (meta to the nitrogen).
Fluorine (F) at position 5 (para to the nitrogen).
Methoxy (-OCH₃) at position 2 (ortho to the nitrogen).

Key Properties

Molecular Formula: C₆H₅BrFNO.
Molecular Weight: ~220.01 g/mol.
Appearance: Likely a white to off-white crystalline solid.
Applications:
Pharmaceutical Intermediate: Used in drug discovery, particularly in synthesizing bioactive molecules (e.g., kinase inhibitors).
Agrochemicals: May act as a building block for pesticides or herbicides.
Material Science: Potential use in ligands for catalysis.

Synthesis

Typically prepared via:

Halogenation (bromination/fluorination) of a pre-functionalized pyridine.

Methoxy group introduction via nucleophilic substitution (e.g., using methylating agents like CH₃I).

Safety

May be irritant (due to bromine/fluorine).
Handle with gloves/eye protection in a fume hood.

This compound’s halogen and methoxy groups enhance reactivity for cross-coupling reactions (e.g., Suzuki-Miyaura), making it valuable in organic synthesis.

Article illustration

Company Profile Introduction

Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical & its intermediates, Food/Feed additives, Fine chemicals in distributing the products of our own company and affiliated enterprises, are the members of Hubei E-commerce Chamber. Our company has professional persons who major in chemical R&D and sicentific management, supply fine chemical products with high quality and close service, also supply custom-tailored products according to our clients' requirement. We have a positive and self-motivated management work team with a common philosophy, caring and commitment through teamwork, our team strive to achieve success in delighting our clients and ourselves. Since Wuhan Fortuna Chemical Co., Ltd founded, we continuously innovate our products and improve our service, sales network. Hence, we initiate the first sale mode on net in China, which is the retail trade of small package bring along wholesale of diversified management modes. Our products are exported widely to South Korea, Vietnam, Australia, Europe and South America, highly recommended by our clients.We insist on the management creed “Market is our compass, Quality is our life, Credit is our soul”. Clients’ trust is our forward powder, their satisfaction is our struggling goal.

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