3,4-O-Isopropylidene-shikimic acid NEW
| Price | $68 | $168 | $248 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-11-10 |
Product Details
| Product Name: 3,4-O-Isopropylidene-shikimic acid | CAS No.: 183075-03-8 |
| Purity: 99.47% | Supply Ability: 10g |
| Release date: 2025/11/10 |
Product Introduction
Bioactivity
| Name | 3,4-O-Isopropylidene-shikimic acid |
| Description | 3,4-O-Isopropylidene-shikimic acid (3,4-O-Isopropylidene shikimic acid) exhibits significant anti-inflammatory, anti-thrombosis, antioxidant, and analgesic effects, and provides protective benefits against trinitrobenzenesulfonic acid-induced experimental colitis in rats, likely because of its antioxidant properties. |
| In vitro | 3,4-O-Isopropylidene shikimic acid (ISA,1-100 micromol/L) effectively reduced PMN adhesion to TNF-alpha-induced HUVEC with the inhibitory rate from 17.2 % to 53.5 % and exerted no effect on PMN adhesion to normal HUVEC. Adhesion molecule ICAM-1 surface protein and mRNA expression induced by TNF-alpha (400 kU/L) were significantly inhibited by ISA. In addition, the cell viability of HUVEC was unchanged 48 h after treatment with ISA[1] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 60 mg/mL (280.09 mM), Sonication is recommended. 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (9.34 mM), Sonication is recommended. |
| Keywords | shikimic | PGE | NOSynthase | NOS | NO Synthase | Inhibitor | inhibit | antioxidant | anti-inflammatory | acid | 3,4-O-Isopropylidene-shikimic acid | 3,4OIsopropylideneshikimic acid | 3,4 O Isopropylidene shikimic acid |
| Inhibitors Related | Aminoguanidine hydrochloride | L-NAME hydrochloride | Chondroitin sulfate | Mifepristone | 2,4-Diamino-6-hydroxypyrimidine | Dexamethasone acetate | S-Methylisothiourea sulfate | L-Arginine | Nitroarginine | Ethyl cinnamate | Diallyl disulfide | L-Arginine hydrochloride |
| Related Compound Libraries | Traditional Chinese Medicine Monomer Library | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Selected Plant-Sourced Compound Library | Antioxidant Compound Library | Anti-Inflammatory Traditional Chinese Medicine Compound Library | Natural Product Library | Neuroprotective Compound Library | Natural Product Library for HTS | Immunology/Inflammation Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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