360A iodide NEW
| Price | $747 | $1390 |
| Package | 50mg | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-10-28 |
Product Details
| Product Name: 360A iodide | CAS No.: 737763-37-0 |
| Supply Ability: 10g | Release date: 2025/10/28 |
Product Introduction
Bioactivity
| Name | 360A iodide |
| Description | 360A iodide is a selective G-quadruplex stabilizer that inhibits telomerase activity (IC50: 300 nM in TRAP-G4 assay). |
| Cell Research | In brief, cells are seeded at various densities, depending on cell type (0.25-4 × 10^3 cells/well in 100?μL complete medium), in 96-well culture plates and treated with various concentrations (0.1-20?μM) of 360A or the corresponding concentrations of DMSO (control wells) for 3 or 7 days at 37°C in an atmosphere containing 5% CO2. For 7-day assays, the medium is changed on day 3. Experiments are performed in triplicate [1]. |
| In vitro | 360A reduces the viability of glioma cell lines, such as CB193, T98G, U118-MG, SAOS-2, and Primary astrocytes, with IC50s of 3.9 μM, 4.8 μM, 8.4 μM, >15 μM and 17.4 μM, respectively [1]. 360A causes Rad51-dependent telomere aberrations preferentially involving the lagging strand telomeres, including telomere losses or telomere doublets, and induces DNA-PKcs-dependent sister telomere fusions [2]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 2 mg/mL (2.84 mM), Sonication is recommended. |
| Keywords | Telomerase | 360A iodide | 360A Iodide | 360 A Iodide |
| Inhibitors Related | 5-Fluorouracil | Quinizarin | Adenine hemisulfate | Levofloxacin hydrochloride | Rifaximin | Guanidine hydrochloride | Methotrexate disodium | Adenine | Carbazole | Thymidine | Docosanoic acid | Dihydromyricetin |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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