4-Methylumbelliferyl oleate NEW
| Price | $30 | $43 | $68 |
| Package | 5mg | 10mg | 25mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-09-22 |
Product Details
| Product Name: 4-Methylumbelliferyl oleate | CAS No.: 18323-58-5 |
| Purity: 98.02% | Supply Ability: 10g |
| Release date: 2025/09/22 |
Product Introduction
Bioactivity
| Name | 4-Methylumbelliferyl oleate |
| Description | 4-Methylumbelliferyl oleate is a fluorescent substrate for lipases (Ex/Em=320/450 nm), which can be cleaved by lipase and can be used to measure pancreatic inhibitory activity. |
| Kinase Assay | 4-Methylumbelliferyl (4-MU) oleate as a substrate to measure the inhibitory activity of compounds on pancreatic lipase a. Reagent preparation: The reaction mixture includes 50 µL of 0.1 mM 4-MU oleate, 20 µL of McIlvane buffer (0.1 M citric acid-Na2HPO4, pH 7.4) and 5 µL of sample solution. b. Operation steps: 1. Add 25 µL of porcine pancreatic lipase to the reaction mixture and adjust the total volume to 0.1 mL. 2. After the mixture is incubated at 37°C for 10 minutes, the amount of 4-MU released by lipase is measured by using a fluorescence multifunctional detector at an excitation wavelength of 320 nm and an emission wavelength of 450 nm. |
| In vitro | Pancreatic lipase inhibitory activity was assessed by employing 4-Methylumbelliferyl (4-MU) oleate as the substrate. The assay mixture contained 0.1 mM 4-MU oleate (50 µL), McIlvaine buffer (20 µL of 0.1 M citrate-Na2HPO4, pH 7.4), and the test sample (5 µL). This was followed by the addition of porcine pancreatic lipase (25 µL), adjusting the total volume to 0.1 mL. Post incubation at 37℃ for 10 minutes, lipase-catalyzed liberation of 4-MU was quantified using fluorescence multi-detection reader at excitation and emission wavelengths of 320 nm and 450 nm, respectively [1]. |
| Storage | keep away from moisture | store at -20°C | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 80 mg/mL (181.57 mM), Sonication is recommended. |
| Related Compound Libraries | Human Metabolite Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
You may like
Recommended supplier
| Product name | Price | Suppliers | Update time | |
|---|---|---|---|---|
| $0.00/25KG |
VIP6Y
|
Hebei Mujin Biotechnology Co.,Ltd
|
2025-09-16 | |
| $/ |
VIP5Y
|
RongNa Biotechnology Co.,Ltd
|
2025-04-29 | |
| $0.00/10G |
VIP5Y
|
WUHAN FORTUNA CHEMICAL CO., LTD
|
2023-02-15 |
United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
INQUIRY