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Postion:Product Catalog >Organic Chemistry>Ketones>5-(2-Fluorophenyl)-1H-pyrrole-3-carbaldehyde
  • 5-(2-Fluorophenyl)-1H-pyrrole-3-carbaldehyde
  • 5-(2-Fluorophenyl)-1H-pyrrole-3-carbaldehyde
  • 5-(2-Fluorophenyl)-1H-pyrrole-3-carbaldehyde
  • 5-(2-Fluorophenyl)-1H-pyrrole-3-carbaldehyde
  • 5-(2-Fluorophenyl)-1H-pyrrole-3-carbaldehyde

5-(2-Fluorophenyl)-1H-pyrrole-3-carbaldehyde NEW

Price Get Latest Price
Package 1KG 5KG 25KG
Min. Order: 1KG
Supply Ability: 20 T each week
Update Time: 2023-08-11

Product Details

Product Name: 5-(2-Fluorophenyl)-1H-pyrrole-3-carbaldehyde CAS No.: 881674-56-2
EC-No.: 809-913-6 Min. Order: 1KG
Purity: 98%~99% Supply Ability: 20 T each week
Release date: 2023/08/11

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Product Name:5-(2-Fluorophenyl)-1H-pyrrole-3-carbaldehyde
Synonyms:1H-Pyrrole-3-carboxaldehyde, 5-(2-fluorophenyl)-;5-(2-fluorophenyl)-1H-pyrrole-3-carbaldehyde;5-(2-Fluorophenyl)-1H-pyrrole-3-carbal...;5-(2-Fluorophenyl)-1H-pyrrole-3-carboxaldehyde;1H-Pyrrole-3-carboxaldehyde, 5-(2-fluorophenyl)-1H-pyrrole-;TAK438 Impurity 54;1H-Pyrrole-3-carboxaldehyde, 5-(2-fluorophenyl)-1H-pyrrole-3-carbaldehyde;TAK-438( Vonoprazan fumarate) intermediate 3
Product Categories:Vonoprazan;Pharmaceutical Intermediates;881674-56-2
Mol File:881674-56-2.mol
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5-(2-Fluorophenyl)-1H-pyrrole-3-carbaldehyde Chemical Properties
Melting point 133 °C
Boiling point 370.6±32.0 °C(Predicted)
density 1.270±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
solubility Chloroform (Slightly, Sonicated), DMSO (Slightly), Methanol (Slightly)
form Solid
color Light Brown to Brown

Safety Information
HS Code 2933998090
MSDS Information

5-(2-Fluorophenyl)-1H-pyrrole-3-carbaldehyde Usage And Synthesis
Chemical PropertiesLight orange to Yellow to Green powder to crystal.
Uses5-(2-Fluorophenyl)-1H-pyrrole-3-carbaldehyde acts as a reagent in the synthetic preparation of novel pyrrole derivatives as potassium-competitive acid blocker (P-CAB).
Application5-(2-Fluorophenyl)-1H-pyrrole-3-carbaldehyde is a potassium ion-competitive acid blocker used in therapy Acid-related diseases, gastric ulcer, duodenal ulcer, reflux esophagitis, etc.
PreparationSynthesis of 5-(2-Fluorophenyl)-1H-pyrrole-3-carbaldehyde: Using pyrrole as raw material, after being protected by N-alkylation of triisopropylsilyl chloride, it is then reacted with Vilsmeier reagent to obtain 1H-Pyrrole-3-carbaldehyde, which is then purified by N-bromosuccinimide (NBS) bromination and 2-fluorophenylboronic acid for Suzuki coupling reaction to obtain crude 5-(2-Fluorophenyl)-1H-pyrrole-3-carbaldehyde, which was purified with toluene. The total yield was 35.5%.

Company Profile Introduction

Shandong Huisheng Import & Export Co., Ltd. is located in Jinan city, Shandong Province, is a collection of domestic trade, international trade in one of the diversified services company. Our goal is to provide customers with high quality solutions and one-stop purchasing experience. At present, the company business scope involves five areas: Organic chemical raw materials, inorganic chemical raw materials, fine chemical raw materials, dangerous chemicals and green environmental protection chemical technology project promotion, and we has also established good relations of cooperation with several well-known enterprises and won the strong support of extensive trust from the new and old customers. Products are widely used in automobile, household appliances, office supplies, mobile phone accessories, routers, food, medical and other fields. At present, our business covers 30 countries, and our customers mainly come from Australia, New Zealand, Canada, Germany, France, Poland, South Korea, Russia, Bangladesh, Vietnam, Kazakhstan, India, Ghana, Nigeria, South Africa, Egypt and other more than 30 countries. The company has a sound quality management system and advanced professional equipment, with a positive attitude to meet the changing needs of customers. We take "quality products, quality service, competitive price, timely delivery" as the purpose, looking forward to greater cooperation with overseas customers on the basis of mutual benefit. Our company provides a wide range of products to meet your various needs. Since its inception, the company has always adhered to the "quality first, customer first, reputation first" business policy, wholeheartedly meet the potential needs of our customers. Under the irresistible situation of economic globalization, our company is willing to cooperate sincerely with enterprises around the world to achieve a win-win situation.

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