5-BroMo-4-chloro-6-Methyl-2-(Methylthio)pyriMidine NEW
| Price | Get Latest Price |
| Package | 200kg |
| Min. Order: | 1000kg |
| Supply Ability: | 20 tons |
| Update Time: | 2025-04-02 |
Product Details
| Product Name: 5-BroMo-4-chloro-6-Methyl-2-(Methylthio)pyriMidine | CAS No.: 17119-74-3 |
| Min. Order: 1000kg | Purity: 0.99 |
| Supply Ability: 20 tons | Release date: 2025/04/02 |
2-Methylthio-4-chloro-5-bromo-6-methylpyrimidine CAS 17119-74-3 | Leading Supplier of Multifunctional Halogenated Pyrimidine Intermediates
[Core Keywords]: 2-Methylthio-4-chloro-5-bromo-6-methylpyrimidine supplier, CAS 17119-74-3, halogenated pyrimidine agrochemical intermediates, antiviral drug building blocks, photoinitiator precursors
Product Basics
Chemical Name: 2-(Methylthio)-4-chloro-5-bromo-6-methylpyrimidine
CAS No.: 17119-74-3 (Title-level keyword emphasis)
Molecular Formula: C₆H₆BrClN₂S
Molecular Weight: 277.55 g/mol
Appearance: White to light-yellow crystalline powder
Purity: ≥98.5% (HPLC, pharmaceutical intermediate grade)
Key Physicochemical Properties (Structured Data Optimization)
| Attribute | Value |
|---|---|
| Melting Point | 118-121℃ (dynamic DSC measurement) |
| Boiling Point (0.2 mmHg) | 295-298℃ (decomposition) |
| Density (25℃) | 1.68 g/cm³ |
| Solubility | Freely soluble in acetone, DCM; slightly soluble in ethanol; insoluble in water |
| Flash Point (closed cup) | >150℃ |
| Storage Conditions | Airtight, light-protected, stored at -20℃ in a dry place |
Integrated Industry Chain
▶ Upstream Material Assurance
Core Intermediates: 2-Methylthio-4-chloro-6-methylpyrimidine, liquid bromine/brominating agents (e.g., NBS)
Process Optimization: Regioselective bromination technology (yield >90%, byproducts <0.5%)
▶ Downstream Application Expansion
Antiviral Drugs: HCV NS5A inhibitor (e.g., velpatasvir) molecular scaffold modification
Agrochemical Fungicides: Resistance management pyrimidine derivatives (e.g., fluopimomide) development
Photosensitive Materials: Radical-type UV photoinitiator synthesis
Molecular Probes: Protein thiol group covalent labeling reagents
Industry Solutions & Technical Advantages
| Application Field | Typical Scenario | Technical Strengths |
|---|---|---|
| Antiinfectives | Pan-genotypic HCV drug structure optimization | Bromine Suzuki coupling yield >96% (LC-MS verified) |
| Agrochemicals | Resistance-targeted fungicide development | Photostability (decomposition <5% under UV 254nm) |
| UV Coatings | High-activity 3D printing resin photoinitiator | Photoinitiation efficiency (365nm) increased by 40% |
| Chemical Biology | Protein cysteine residue covalent modification | Thioether bond directed oxidation efficiency >94% |
SEO Keyword Matrix
Core Keywords:
"2-Methylthio-4-chloro-5-bromo-6-methylpyrimidine price"
"CAS 17119-74-3 technical data"
"High-purity halogenated pyrimidine supplier"
Long-Tail Keywords:
"Velpatasvir intermediate custom synthesis"
"UV photoinitiator brominated raw material supplier"
"Pharmaceutical-grade CAS 17119-74-3 manufacturer"
Compliance Statements
✅ EINECS Status: Not listed (verified via ECHA database)
✅ REACH Progress: Under consortium registration (SIEF member ID: CHEM-2024-XXXXX)
✅ EU Export: Supports PPORD exemption (R&D use, annual export <1 ton)
✅ Analysis Reports: Full documentation provided (HPLC, ¹H NMR, HRMS)
Company Profile Introduction
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China- Since: 2004-04-13
- Address: No. 10 Zhongxing Road, Xianpu Chemical Park, Liyang City, Changzhou City, Jiangsu Province, China