5-Chloro-2-methylpyrimidine NEW
| Price | Get Latest Price |
| Package | 200kg |
| Min. Order: | 1000kg |
| Supply Ability: | 20 tons |
| Update Time: | 2025-04-02 |
Product Details
| Product Name: 5-Chloro-2-methylpyrimidine | CAS No.: 54198-89-9 |
| Min. Order: 1000kg | Purity: 0.99 |
| Supply Ability: 20 tons | Release date: 2025/04/02 |
2-Methyl-5-chloropyrimidine CAS 54198-89-9 | Leading Supplier of High-Activity Chloropyrimidine Intermediates
[Core Keywords]: 2-Methyl-5-chloropyrimidine supplier, CAS 54198-89-9, chloropyrimidine pharmaceutical intermediates, agrochemical fungicide building blocks, organic ligand precursors
Product Basics
Chemical Name: 2-Methyl-5-chloropyrimidine
CAS No.: 54198-89-9 (Title-level keyword emphasis)
Molecular Formula: C₅H₅ClN₂
Molecular Weight: 128.56 g/mol
Appearance: Colorless to light-yellow transparent liquid
Purity: ≥98.5% (GC, industrial/pharmaceutical grade available)
Key Physicochemical Properties (Structured Data Optimization)
| Attribute | Value |
|---|---|
| Melting Point | -15℃ |
| Boiling Point (atm) | 185-188℃ |
| Density (25℃) | 1.22 g/cm³ |
| Refractive Index (n²⁰/D) | 1.528-1.532 |
| Solubility | Freely soluble in ethanol, acetone; slightly soluble in water (~1.2%) |
| Flash Point (closed cup) | 78℃ |
| Storage Conditions | Airtight, light-protected, stored in a cool ventilated area |
Integrated Industry Chain
▶ Upstream Material Assurance
Core Intermediates: 2-Methylpyrimidine-5-ol, thionyl chloride (SOCl₂)
Process Optimization: Low-temperature selective chlorination technology (yield >95%, byproducts <0.3%)
▶ Downstream Application Expansion
Antiviral Drugs: Key fragment for HCV NS5A inhibitors (e.g., daclatasvir)
Agrochemical Fungicides: Molecular modification of strobilurin-based compounds
Functional Materials: Organic semiconductor dopant synthesis
Molecular Probes: Development of nucleic acid base analogs
Industry Solutions & Technical Advantages
| Application Field | Typical Scenario | Technical Strengths |
|---|---|---|
| Antiinfectives | Daclatasvir analog synthesis | Chlorine Suzuki coupling yield >97% (LC-MS verified) |
| Agrochemicals | Resistance-management fungicide R&D | Hydrolytic stability >90% at pH 5-9 |
| OLED Materials | Hole-blocking ETL material fabrication | Purity ≥99.9% (molecular distillation process) |
| Chemical Biology | DNA/RNA-targeted covalent modifiers | Pyrimidine ring-directed functionalization efficiency >93% |
SEO Keyword Matrix
Core Keywords:
"2-Methyl-5-chloropyrimidine price"
"CAS 54198-89-9 technical data"
"High-activity chloropyrimidine supplier"
Long-Tail Keywords:
"HCV NS5A inhibitor intermediate manufacturer"
"Strobilurin fungicide raw material supplier"
"Pharmaceutical-grade CAS 54198-89-9 producer"
Compliance Statements
✅ EINECS Status: Not listed (verified via ECHA database)
✅ REACH Progress: Under consortium registration (SIEF member ID: CHEM-2024-XXXXX)
✅ EU Export: Supports PPORD exemption (R&D use, annual export <1 ton)
✅ Analysis Reports: Full documentation provided (GC, ¹H NMR, elemental analysis)
Company Profile Introduction
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China- Since: 2004-04-13
- Address: No. 10 Zhongxing Road, Xianpu Chemical Park, Liyang City, Changzhou City, Jiangsu Province, China