Product Details
Product Name:
D-ERYTHRO-SPHINGOSINE |
CAS No.:
123-78-4 |
Min. Order:
1g |
Purity:
99% |
Supply Ability:
100KG |
Release date:
2019/07/06 |
Product::
AD68 |
D-ERYTHRO-SPHINGOSINE Basic information |
Product Name: |
D-ERYTHRO-SPHINGOSINE |
Synonyms: |
SPHINGOSINE;SPHINGOSINE, C18 CHAIN;SPHINGOSINE, D-ERYTHRO;TRANS D-THREO-SPHINGOSINE;TRANS D-ERYTHRO-SPHINGOSINE;TRANS-D-ERYTHRO-2-AMINO-4-OCTADECENE-1,3-DIOL;BRAIN SPHINGOSINE;BRAIN, BOVINE |
CAS: |
123-78-4 |
MF: |
C18H37NO2 |
MW: |
299.49 |
EINECS: |
204-651-3 |
Product Categories: |
Mixed Fatty Acids;Fatty Acid Derivatives & Lipids;Glycerols;Inhibitors;Protein Kinase Inhibitors and Activators;Protein Kinase;Amines |
Mol File: |
123-78-4.mol |
|
|
D-ERYTHRO-SPHINGOSINE Chemical Properties |
Melting point |
81-82 °C |
Boiling point |
440.8°C (rough estimate) |
density |
0.9758 (rough estimate) |
refractive index |
1.5000 (estimate) |
storage temp. |
−20°C |
solubility |
chloroform: 20 mg/mL, clear, colorless to very faintly yellow |
form |
Powder or Waxy Solid |
color |
White to cream |
Merck |
14,8747 |
Stability: |
Stable. Incompatible with strong acids, strong bases, strong oxidizing agents. |
CAS DataBase Reference |
123-78-4 |
Safety Statements |
22-24/25 |
WGK Germany |
3 |
F |
1-8-10 |
HS Code |
29221985 |
Provider |
Language |
ACROS |
English |
SigmaAldrich |
English |
|
D-ERYTHRO-SPHINGOSINE Usage And Synthesis |
Chemical Properties |
White Crystalline Solid |
Uses |
Selective inhibitor of protein kinase C activity and phorbol dibutyrate binding in vitro in human platelets; does not inhibit protein kinase A or myosin light chain kinase; inhibits calmodulin-dependent enzymes; natural isomer of sphingosine |
Biological Activity |
Inhibitor of protein kinase C and calmodulin-dependent enzymes, but may stimulate mast cells by activation of protein kinase C. |
Purification Methods |
D-Sphingosine is purified by recrystallisation from EtOAc, Et2O or pet ether (60-80o). It is insoluble in H2O but is soluble in Me2CO, EtOH and MeOH. It has IR bands at 1590 and 875 cm-1, and is characterised as the tribenzoate m 122-123o (from 95% EtOH). [Tipton Biochemical Preparations 9 127 1962.] |
Company Profile Introduction
Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals.
Mainly deals in the sales of:
Pharmaceutical intermediates
OLED intermediates:
Pharmaceutical intermediates;
OLED intermediates;
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