CYTOCHALASIN D
| Price | $1 |
| Package | 1kg |
| Min. Order: | 1g |
| Supply Ability: | 100KG |
| Update Time: | 2019-07-06 |
Product Details
| Product Name: CYTOCHALASIN D | CAS No.: 22144-77-0 |
| Min. Order: 1g | Purity: 99% |
| Supply Ability: 100KG | Release date: 2019/07/06 |
| Product:: AD68 |
| CYTOCHALASIN D Basic information |
| Product Name: | CYTOCHALASIN D |
| Synonyms: | ZYGOSPORIN A;CYTOCHALASIN D;CYTOCHALASIN D, ZYGOSPORIUM MANSONII;CYTOCHALASIN D, ZYGUSPORIUM MANSONII;(7S,13E,16S,18R,19E,21R)-21-(ACETYLOXY)-7,18-DIHYDROXY-16,18-DIMETHYL-10-PHENYL[11]CYTOCHALASA-6(12),13,19-TRIENE-1,17-DIONE;(11)cytochalasa-6(12),13,19-triene-1,17-dione,21-(acetyloxy)-7,18-dihydroxy-16;,12,15-decahydro-6,12,15-trihydroxy-4,10,12-trimethyl-5-methylene-,15-acetate;,18-dimethyl-10-phenyl-,(7s,13e,16s,18r,19e,21r)- |
| CAS: | 22144-77-0 |
| MF: | C30H37NO6 |
| MW: | 507.62 |
| EINECS: | 244-804-1 |
| Product Categories: | Caspases/Apoptosis;antibiotic |
| Mol File: | 22144-77-0.mol |
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| CYTOCHALASIN D Chemical Properties |
| Melting point | 255-260°C |
| Boiling point | 595.84°C (rough estimate) |
| density | 1.1764 (rough estimate) |
| refractive index | 1.6310 (estimate) |
| Fp | 87℃ |
| storage temp. | −20°C |
| solubility | DMSO: soluble |
| Safety Information |
| Hazard Codes | T |
| Risk Statements | 25-63 |
| Safety Statements | 36/37-45 |
| RIDADR | UN 1544 6.1/PG 2 |
| WGK Germany | 3 |
| RTECS | GZ4850000 |
| HazardClass | 6.1(a) |
| PackingGroup | I |
| MSDS Information |
| Provider | Language |
|---|---|
| SigmaAldrich | English |
| CYTOCHALASIN D Usage And Synthesis |
| Chemical Properties | Powder |
| Uses | Cytochalasin D acts as an anti-hypertensive drug acting on human intestinal epithelial caco-2 cells. Also has activity in HMG-CoA reductase inhibitors used in the lowering of cholesterol. Actin inhib itor, actin polymerization inhibitor affecting cell movement, growth, phagocytosis and even secretion. |
| Uses | Cytochalasin D is the most studied of the cytochalasins. Like most of the members of this mycotoxin class, cytochalasin D exhibits potent inhibition of actin filament function leading to cell death by apoptosis. This led to early investigation of the metabolite as an antitumour agent. Cytochalasin D has become one of the standard cellular probes for investigating the role of actin in cell biology. |
| Uses | Cytochalasin D is the most studied of the cytochalasins. Like most of the members of this mycotoxin class, cytochalasin D exhibits potent inhibition of actin filament function leading to cell death by apoptosis. This led to early investigation of the metabolite as an antitumor agent. Cytochalasin D has become one of the standard cellular probes for investigating the role of actin in cell biology. |
| Uses | A cell cycle arresting compound used in actin polymerization studies and cytological research |
| Definition | ChEBI: An organic heterotricyclic compound that is a mycotoxin produced by Helminthosporium and other moulds which is cell permeable and a potent inhibitor of actin polymerisation and DNA synthesis. |
| General Description | Needles or fluffy white powder. |
| Reactivity Profile | CYTOCHALASIN D may be sensitive to exposure to heat. CYTOCHALASIN D can react with strong oxidizing agents, strong acids and strong bases. . |
| Fire Hazard | Flash point data for CYTOCHALASIN D are not available; however, CYTOCHALASIN D is probably combustible. |
| Biological Activity | Potent disruptor of actin filament function. Alters tight junction permeability. Unlike cytochalasin B, does not inhibit monosaccharide transport across the plasma membrane. |
| Safety Profile | Poison by ingestion, subcutaneous, and intraperitoneal routes. An experimental teratogen. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx. |
Company Profile Introduction
Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals.
Mainly deals in the sales of:
Pharmaceutical intermediates
OLED intermediates：
Pharmaceutical intermediates;
OLED intermediates;
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China- Since: 2014-12-17
- Address: Zhengzhou High tech Zone, Henan Province, China
INQUIRY
杨俊青
sales@coreychem.com
sales@coreychem.com