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Postion:Product Catalog >Pharmaceutical intermediates>Heterocyclic compound>Pyridine compound>Ethylpyridine>Alpelisib (BYL719)
Alpelisib (BYL719)
  • Alpelisib (BYL719)

Alpelisib (BYL719)

Price Get Latest Price
Package 1g 1KG
Min. Order: 10mg
Supply Ability: 1~10kg
Update Time: 2023-09-13

Product Details

Product Name: Alpelisib (BYL719) CAS No.: 1217486-61-7
Min. Order: 10mg Purity: 99.0%HPLC
Supply Ability: 1~10kg Release date: 2023/09/13

Alpelisib (BYL-719) potently inhibits the 2 most common PIK3CA somatic mutations (H1047R, E545K; IC50s~4 nM). Alpelisib potently inhibits Akt phosphorylation in cells transformed with PI3Kα (IC50=74±15 nM) and shows significant reduced inhibitory activity in PI3Kβ or PI3Kδ isoforms transformed cells (≥15-fold compared with PI3Kα)

Company Profile Introduction

Byl719,Ixabepilone,Epothilone B etc.Byl719,Ixabepilone,Epothilone B etc. Byl719,Ixabepilone,Epothilone B etc.Byl719,Ixabepilone,Epothilone B etc.

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