8-M-PDOT NEW
| Price | $30 | $64 | $118 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-10-27 |
Product Details
| Product Name: 8-M-PDOT | CAS No.: 134865-70-6 |
| Purity: 99.54% | Supply Ability: 10g |
| Release date: 2025/10/27 |
Product Introduction
Bioactivity
| Name | 8-M-PDOT |
| Description | 8-M-PDOT (AH-002) is a selective and potent melatonin MT2 receptor agonist that also inhibits MT1 receptors. 8-M-PDOT exhibits anxiolytic activity and can be used to study MT2-induced neuropathic pain. |
| Animal Research | Animal Model: Male Wistar rats (280-320 g) with Rotenone [2]. Dosage: 10 μg/μL. Administration: Administrated into the dorsal striatum by bilateral cannulas; for 30 minutes |
| In vivo | Treatment with 8-M-PDOT (10 µg/µL; administered into the dorsal striatum by bilateral cannulas; for 30 minutes; male Wistar rats) demonstrates an anxiolytic-like effect[2]. |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 50 mg/mL (214.31 mM), Sonication is recommended. |
| Keywords | MTReceptor | MT2 receptor | MT1 receptor | MT Receptor | AH002 | AH 002 | 8-M-PDOT | 8MPDOT | 8 M PDOT |
| Inhibitors Related | Agomelatine hydrochloride | N-ACETYLTRYPTAMINE | Agomelatine | Ramelteon | ACH-000143 | glycine | 6-Chloromelatonin | 4-P-PDOT | Tasimelteon | Melatonin | Piromelatine | Luzindole |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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