ACHN-975 TFA NEW
| Price | $1100 | $1430 | $2170 |
| Package | 25mg | 50mg | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-12-22 |
Product Details
| Product Name: ACHN-975 TFA | CAS No.: 1410809-37-8 |
| Supply Ability: 10g | Release date: 2025/12/22 |
Product Introduction
Bioactivity
| Name | ACHN-975 TFA |
| Description | ACHN-975 TFA is a selective inhibitor of the bacterial enzyme LpxC with nM-level activity. It exhibits antimicrobial activity with MIC values below 1 μg/mL against multiple Gram-negative bacteria. |
| Animal Research | Animal Model: Neutropenic mouse thigh model with P. aeruginosa ATCC 27853. Dosage: 5-30 mg/kg. Administration: i.p.; single dose [2] |
| In vitro | ACHN-975 TFA demonstrated potent inhibitory activity against all tested Pseudomonas aeruginosa isolates, with MIC50 and MIC90 values of 0.06 and 0.25 μg/ml, respectively [2]. |
| In vivo | In the neutropenic murine thigh infection model, ACHN-975 TFA at doses of 10 mg/kg and 30 mg/kg significantly reduced bacterial counts within 4 hours and maintained them below the detection limit for 24 hours [2]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 80.00 mg/mL (165.48 mM), Sonication is recommended. |
| Keywords | ACHN-975 TFA | ACHN 975 TFA |
| Inhibitors Related | Neomycin sulfate | Adipic dihydrazide | Levulinic acid | Kanamycin sulfate | D(+)-Raffinose pentahydrate | Sulfamethoxazole sodium | Terbinafine hydrochloride | Metronidazole | Doxycycline | Dimethyl sulfoxide | Sodium diacetate | BES |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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