Antitumor agent-115 NEW
| Price | $1520 | $1980 | $2500 |
| Package | 25mg | 50mg | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-08-21 |
Product Details
| Product Name: Antitumor agent-115 | CAS No.: 2759277-20-6 |
| Supply Ability: 10g | Release date: 2025/08/21 |
Product Introduction
Bioactivity
| Name | Antitumor agent-115 |
| Description | Antitumor agent-115 (SS-12) is a potent anti-tumor compound with an IC50 range of 0.34 μM-24.14 μM against the 4T1 mouse breast cancer cell line. It impedes the cell cycle, diminishes mitochondrial membrane potential, and triggers apoptosis, with an IC50 for cell viability spanning 8-25 μmol/L. This compound is applicable in breast cancer research [1]. |
| In vitro | Antitumor agent-115 (SS-12) primarily induces apoptosis in 4T1 cells by causing G0/G1 phase cell cycle arrest at 1.25 μM, 10 μM, and 40 μM concentrations over 24 hours [1]. At higher concentrations (15 μM, 30 μM, and 60 μM) for the same duration, it inhibits migration and invasion of 4T1 cells. Furthermore, at 10 μM over 24 hours, it induces apoptosis via the mitochondrial pathway [1]. |
| In vivo | Antitumor agent-115 (SS-12) exhibits high bioavailability in rats at a dose of 10 mg stachydrine/kg equivalent (200 μL, oral administration) and demonstrates antitumor activity in a mouse breast cancer model at a dosage of 0.1 mL/10 g (oral administration), improving the morphological structure of the spleen in these mice [1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Inhibitors Related | Stavudine | 5-Fluorouracil | Flubendazole | Cysteamine hydrochloride | Myricetin | Sodium 4-phenylbutyrate | L-Ascorbic acid | L-Glutamic acid | Tributyrin | L-Ascorbic acid sodium salt | Alginic acid | Dextran sulfate sodium salt (MW 5000) |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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