APF NEW
| Price | $243 | $768 |
| Package | 1mg | 5mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2026-04-23 |
Product Details
| Product Name: APF | CAS No.: 359010-70-1 |
| Purity: 99.97% | Supply Ability: 10g |
| Release date: 2026/04/23 |
Product Introduction
Bioactivity
| Name | APF |
| Description | APF is an aromatic amino-fluorescein derivative that serves as a highly specific fluorescent probe for detecting highly reactive radicals, exhibiting low intrinsic fluorescence but converting into strongly fluorescent fluorescein upon oxidation by hydroxyl radicals, hypochlorite ions, and selected peroxidase intermediates. APF remain unreactive to nitric oxide and hydrogen peroxide, while with fluorescein displays excitation and emission maxima of 490 nm and 515 nm, respectively, enabling sensitive visualization of oxidative stress in biological systems. |
| In vitro | In cellular assays for detecting Reactive Oxygen Species (ROS), APF was utilized at a working concentration of 1-10 μM. The probe effectively stained both suspension and adherent cells when incubated at 37°C for 20-60 minutes in serum-free media or PBS. This staining allowed for subsequent detection via fluorescence microscopy or flow cytometry [1]. |
| Storage | Store at -20°C Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMF : 20 mg/mL (47.23 mM), Sonication is recommended. DMSO : 8 mg/mL (18.89 mM), Sonication is recommended. Ethanol:PBS (pH 7.2)(1:3) : 0.5 mg/mL (1.18 mM), Sonication is recommended. Ethanol : 10 mg/mL (23.62 mM), Sonication is recommended. |
| Keywords | APF |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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