ATIC-IN-1 acetate NEW
| Price | Get Latest Price |
| Package | 1removed |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-12-04 |
Product Details
| Product Name: ATIC-IN-1 acetate | Supply Ability: 10g |
| Release date: 2025/12/04 |
Product Introduction
Bioactivity
| Name | ATIC-IN-1 acetate |
| Description | ATIC-IN-1 acetate is an inhibitor of aminoimidazole-carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC) with potential anti-tumor activity. It inhibits AICAR Tfase by disrupting ATIC homo-dimerization. |
| In vitro | ATIC-IN-1 acetate (Compound 14) is an inhibitor of aminoimidazolecarboxamide ribonucleotide translocase/inosine monophosphate cyclization hydrolase (ATIC) dimerization with a Ki value of 685 nM.[1] ATIC-IN-1 acetate (100-500 μM, treated for 48 hours) was able to hinder the proliferation of MCF-7 cells. [1] ATIC-IN-1 acetate (250 μM, 24-72 hours of action) decreases cell division rather than increasing cell death. [1] |
| Storage | keep away from direct sunlight,keep away from moisture,store at low temperature | Shipping with blue ice. |
| Solubility Information | H2O : 40 mg/mL (76.4 mM), Sonication is recommended. DMSO : 40 mg/mL (76.4 mM), Sonication is recommended. |
| Inhibitors Related | Sucrose | Aceglutamide | L-Pyroglutamic acid | Emtricitabine | Levulinic acid | D(+)-Raffinose pentahydrate | D-(+)-Trehalose dihydrate | Glycerol | Thymidine | Gluconate Calcium | Chitosan oligosaccharide | 3-Indoleacetic acid |
| Related Compound Libraries | Bioactive Compound Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library | Anti-Cancer Active Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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