Boc-Leu-Gly-Arg-AMC NEW
| Price | Get Latest Price |
| Package | 1removed |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-11-04 |
Product Details
| Product Name: Boc-Leu-Gly-Arg-AMC | CAS No.: 65147-09-3 |
| Supply Ability: 10g | Release date: 2025/11/04 |
Product Introduction
Bioactivity
| Name | Boc-Leu-Gly-Arg-AMC |
| Description | Boc-Leu-Gly-Arg-AMC is a specific fluorogenic substrate designed for the enzymatic detection and quantification of complement component C3/C5 convertases, coagulation factor Xa, and soybean trypsin-like enzyme activity. Boc-Leu-Gly-Arg-AMC is also susceptible to hydrolysis by macropain, a high molecular weight thiol proteinase isolated from human erythrocytes, making it a versatile tool for enzymatic assays. |
| In vitro | To demonstrate the presence of proteolytic enzymes capable of producing sodifrin in the abdominal gland, polybutoxycarbo-nyl (Boc)-Leu-Gly-Arg-4-methylcoumaryl-7-amide (MCA) and Boc-Leu-Leu-Lys-MCA were used as synthetic substrates. Crude extracts of the abdominal gland hydrolyzed both substrates to release 7-amino-4-methylcoumarin, indicating the presence of enzymes in the gland that generate sodifrin from its precursor molecule. The activity of the extracts to cleave Boc-Leu-Gly-Arg-AMC was optimal at pH 9.0 and 45°C, while the activity to cleave Boc-Leu-Leu-Lys-MCA was optimal at pH 9.0 and 40°C. [1] |
| Storage | keep away from moisture,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 3.3 mg/mL (5.48 mM), Sonication is recommended. DMSO : 80 mg/mL (132.96 mM), Sonication is recommended. H2O : < 0.1 mg/mL (insoluble), Sonication is recommended. |
| Keywords | Boc-Leu-Gly-Arg-AMC | BocLeuGlyArgAMC | Boc Leu Gly Arg AMC |
| Inhibitors Related | Boc-Lys(Boc)-OH | (R)-Methyl 2-amino-2-cyclohexylacetate HCl | Fmoc-Lys(Tfa)-OH | Aceglutamide | DL-Proline | Fmoc-Lys(Z)-OH | Sodium lauroyl glutamate | DL-Isoleucine | Fmoc-Aib-OH | Fmoc-L-aspartic acid | H-Glu(OEt)-OEt.HCl | Fmoc-Lys(Alloc)-OH |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
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