Bosutinib hydrate NEW
| Price | $33 | $53 | $79 |
| Package | 5mg | 10mg | 25mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-12-03 |
Product Details
| Product Name: Bosutinib hydrate | CAS No.: 918639-08-4 |
| Purity: 99.87% | Supply Ability: 10g |
| Release date: 2025/12/03 |
Product Introduction
Bioactivity
| Name | Bosutinib hydrate |
| Description | Bosutinib hydrate (SKI-606 hydrate) is an orally active and potent dual kinase inhibitor of BCR-ABL and Src tyrosine kinases for the study of Philadelphia Chromosome Positive Chronic Granulocytic Leukemia. |
| In vitro | Bosutinib hydrate(SKI-606)was a inhibitor of two Src-related kinases (i.e., Fgr and Lyn with IC50s of 0.174 and 0.850 nmol/L, respectively)[2]. |
| In vivo | Administration of Bosutinib hydrate(SKI-606) at doses of 75 mg/kg twice daily or 150 mg/kg once daily can promote complete regression of human K562 xenografts for up to 40 days[2]. |
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 80 mg/mL (145.86 mM), Sonication is recommended. |
| Keywords | Src | Bcr-Abl | BcrAbl |
| Inhibitors Related | Nintedanib | Imatinib Mesylate | Staurosporine | Pivanex | Dasatinib | GNF-5 | Vodobatinib | Nilotinib monohydrochloride monohydrate | iHCK-37 | MCB-613 | Imatinib | Nocodazole |
| Related Compound Libraries | Failed Clinical Trials Compound Library | Membrane Protein-targeted Compound Library | Kinase Inhibitor Library | Anti-Cancer Clinical Compound Library | Drug Repurposing Compound Library | Inhibitor Library | FDA-Approved Drug Library | FDA-Approved Kinase Inhibitor Library | Anti-Cancer Approved Drug Library | Bioactive Compounds Library Max | Anti-Cancer Active Compound Library | Anti-Cancer Drug Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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