Product Details
| Product Name:
Carabersat |
CAS No.:
184653-84-7 |
| Purity:
100% |
Supply Ability:
10g |
| Release date:
2025/06/13 |
Product Introduction
Bioactivity
| Name | Carabersat |
| Description | Carabersat(SB 204269) is a novel and effective anticonvulsant and antiepileptic agent. |
| In vitro | [3H]Carabersat ([3H]SB 204269) binds to rat forebrain membranes with moderate affinity (Kd 40 nM) and pKi values of 7.3[1]. In mouse forebrain membranes, Carabersat is able to bind, and the binding is saturable and stereospecific, with a Kd of 53 nM. The labeled [3H]Carabersat produces a Kd of 32 nM[2]. Carabersat (SB-204269, 1-100 μM) has no effect on Na+ current in cultured hippocampal neurons. It also shows no effect on action potential discharges evoked by elevating external K+[4]. Structurally related to the benzopyran ATP-sensitive potassium channel (KATP) opener cromakalim, Carabersat (SB-204269) has opposite stereochemistry, and its mechanism of action is not thought to involve KATP[3]. |
| In vivo | Significantly elevating anticonvulsant activity in mice, Carabersat (5b) has been observed[1]. |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Keywords | Carabersat |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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Recommended supplier
| Product name |
Price |
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Suppliers |
Update time |
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$155.00/5mg |
VIP4Y
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TargetMol Chemicals Inc.
|
2025-10-27 |
United States