Product Details
| Product Name:
CC260 |
CAS No.:
2411088-26-9 |
| Supply Ability:
10g |
Release date:
2025/10/27 |
Product Introduction
Bioactivity
| Name | CC260 |
| Description | CC260, a selective inhibitor for PI5P4Kα and PI5P4Kβ with Kis of 40 nM and 30 nM respectively, exhibits minimal to no inhibition against other protein kinases like Plk1 and RSK2. It is applicable in the research of cell energy metabolism, diabetes, and cancer[1]. |
| In vitro | In cultured C2C12 myotubes, CC260 (20 μM) enhances insulin-induced phosphorylation of Akt at Thr-308 and Ser-473, inhibits S6K phosphorylation (Thr-389) mediated by mTORC1, and progressively increases acetyl-CoA carboxylase (ACC) phosphorylation in a dose-dependent manner at concentrations from 2.5 μM to 20 μM[1]. CC260 treatment reduces the survival of BT474 cells under serum starvation, which can be reversed by introducing a PI5P4Kβ-resistant mutant, and also leads to increased glycolytic ATP production in BT474 cells[1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | CC 260 | CC260 | CC-260 |
| Inhibitors Related | Musk ketone | Myricetin | Erucic acid | 4-Methylbenzylidene camphor | (±)-α-Bisabolol | Berberine hydrogen sulphate | Isoprenaline hydrochloride | Thymoquinone | Quercetin | Inavolisib | Berberine sulfate | Apilimod |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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Recommended supplier
| Product name |
Price |
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Suppliers |
Update time |
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$/ |
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Anhui Ruihan Technology Co., Ltd
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2023-08-21 |
United States