Cephaeline dihydrochloride NEW
| Price | Get Latest Price |
| Package | 1removed |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-10-27 |
Product Details
| Product Name: Cephaeline dihydrochloride | CAS No.: 5853-29-2 |
| Purity: 99.67% | Supply Ability: 10g |
| Release date: 2025/10/27 |
Product Introduction
Bioactivity
| Name | Cephaeline dihydrochloride |
| Description | Cephaeline dihydrochloride is a naturally occurring alkaloid that is a selective CYP2D6 inhibitor with an IC50=121 μM. It has an affinity for and oral activity at the 5-HT4 receptor and is capable of inducing vomiting. |
| In vitro | In human liver microsome assays, Cephaeline dihydrochloride demonstrated weak inhibition of major cytochrome P450 (CYP) enzymes. Specifically, Cephaeline dihydrochloride inhibited CYP2D6 with an IC₅₀ of 121 μM and a Ki of 54 μM via competitive inhibition, and CYP3A4 with an IC₅₀ of 1000 μM and a Ki of 355 μM via non-competitive inhibition[1]. |
| Storage | keep away from moisture,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 200.00 mg/mL (370.69 mM), Sonication is recommended. H2O : 100.00 mg/mL (185.35 mM), Sonication is recommended. |
| Keywords | NSC-32944 | CYP2D6 | Cephaeline Dihydrochloride | Cephaeline dihydrochloride | Cephaeline |
| Inhibitors Related | Tebuconazole | Alverine citrate | Naringin dihydrochalcone | Dapoxetine hydrochloride | Apigenin | Fenofibrate | D-Menthol | Naringin | Naringenin | Tauroursodeoxycholate | Chlorzoxazone | Trazodone hydrochloride |
| Related Compound Libraries | Bioactive Compound Library |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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