Product Details
| Product Name:
CVT-12012 |
CAS No.:
1018675-35-8 |
| Purity:
99.91% |
Supply Ability:
10g |
| Release date:
2025/12/05 |
Product Introduction
Bioactivity
| Name | CVT-12012 |
| Description | CVT-12012 is an orally bioavailable inhibitor of stearoyl-CoA desaturase (SCD; IC50 = 6.1 nM in HepG2 cells). |
| In vivo | CVT-12012 is highly potent in a human cell-based (HEPG2) SCD assay (IC(50)=6nM). This compound has 78% oral bioavailability in rats and is preferentially distributed into liver (76 times vs plasma) with relatively low brain penetration[1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 125 mg/mL (287.75 mM), Sonication is recommended.
10% DMSO+40% PEG300+5% Tween 80+45% Saline : 4 mg/mL (9.21 mM), Sonication is recommended.
|
| Keywords | StearoylCoADesaturase(SCD) | StearoylCoADesaturase | Stearoyl-CoA Desaturase (SCD) | StearoylCoA Desaturase (SCD) | Stearoyl-CoA Desaturase | SCD | rat microsomal | Inhibitor | inhibit | human HEPG2 | CVT-12012 | CVT12012 | CVT 12012 |
| Inhibitors Related | SSI-4 | Elemicin | PluriSIn 1 | MK-8245 | SLC13A5-IN-1 | CAY10566 | MF-438 | A939572 | XEN723 | SCD1 inhibitor-4 | GSK1940029 | YTX-465 |
| Related Compound Libraries | Bioactive Compound Library | Anti-Obesity Compound Library | Inhibitor Library | NO PAINS Compound Library | Lipid Metabolism Compound Library | Orally Active Compound Library | Metabolism Compound Library | Bioactive Compounds Library Max | Fluorochemical Library | Anti-Metabolism Disease Compound Library | Anti-COVID-19 Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
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$1980.00/50mg |
VIP2Y
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2025-08-21 |
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$1.00/1g |
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