Compound T9222L(SC) NEW
| Price | Get Latest Price | $970 |
| Package | 2mg | 5mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-08-21 |
Product Details
| Product Name: Compound T9222L(SC) | CAS No.: 2380032-29-9 |
| Supply Ability: 10g | Release date: 2025/08/21 |
Product Introduction
Bioactivity
| Name | Compound T9222L(SC) |
| Description | Emlenoflast sodium (MCC7840 sodium), a sulfonylurea, is a selective NLRP3 inflammasome inhibitor with an IC50 value of less than 100 nM for NLRP3 inflammasome, and can be used in the study of inflammatory diseases. |
| In vitro | Emlenoflast sodium is an MCC950 analogue that exhibits useful activity in inhibiting NLRP3 inflammasome activation with IC50 <100 nM.[1] |
| In vivo | Emlenoflast sodium (4 mg/kg; i.v.; Male C57BL/6 mice) showed t1/2=3.39 h; AUC0-last=107097 ng•h/mL; CL=0.621 mL /min/kg.[2] Emlenoflast sodium (20 mg/kg; p.o.; Male C57BL/6 mice) exhibits good oral bioavailability (67.2%), Cmax (60467 ng/mL) and half-life (5.02 h) in mice.[2] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 216.0 mg/mL (526.2 mM), Sonication is recommended. |
| Keywords | NLRP3 | Emlenoflast sodium |
| Inhibitors Related | Dapansutrile | NOD-IN-1 | MCC950 sodium | Imperatorin | NLRP3-IN-10 | NLRP3-IN-2 | Bergenin | MCC950 | NLRP3-IN-9 | INF39 | ADS032 | Selnoflast |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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| $364.00/10mg |
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ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
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2025-06-21 |
United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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