Estradiol 17-(β-D-Glucuronide) (sodium salt hydrate) NEW
| Price | Get Latest Price | ||
| Package | 5mg | 10mg | 25mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-07-23 |
Product Details
| Product Name: Estradiol 17-(β-D-Glucuronide) (sodium salt hydrate) | Supply Ability: 10g |
| Release date: 2025/07/23 |
Product Introduction
Bioactivity
| Name | Estradiol 17-(β-D-Glucuronide) (sodium salt hydrate) |
| Description | Estradiol 17-(β-D-glucuronide) (E217G) is an estrogen metabolite formed in the liver and subsequently excreted in bile.1It acts as a substrate of the multidrug resistance protein 2 (MRP2; Km= 75 μM), and through MRP2-mediated transport, functions as a cholestatic agent, decreasing bile flow.1,2In addition to binding to the MRP2 transport site, E217G has been shown to bind to an allosteric site that through positive cooperativity activates its own transportviaMRP2 and the transport of other MRP2 substrates, including the non-cholestatic estrogen metabolite, estradiol 3-(β-D-glucuronide) .2,3E217G has also been reported to be transported by MDR1, MRP1, MRP3, MRP4, MRP7, ABCG2 (a breast cancer resistance protein transporter), and the rat organic anion-transporting polypeptides 1-4.2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO:PBS (pH 7.2) (1:1) : 0.5 mg/mL, Sonication is recommended. DMF : 10 mg/mL, Sonication is recommended. DMSO : 20 mg/mL, Sonication is recommended. |
| Keywords | Estradiol 17-(β-D-Glucuronide) | Estradiol 17-(b-D-Glucuronide) | Estradiol 17-(beta-D-Glucuronide) | sodium Hydrate | Estradiol 17 (β D Glucuronide) (sodium salt hydrate) | Estradiol 17(βDGlucuronide) (sodium salt hydrate) |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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