FR-167356 NEW
| Price | $118 | $287 | $392 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-11-10 |
Product Details
| Product Name: FR-167356 | CAS No.: 174185-16-1 |
| Purity: 99.74% | Supply Ability: 10g |
| Release date: 2025/11/10 |
Product Introduction
Bioactivity
| Name | FR-167356 |
| Description | FR-167356 is a specific inhibitor of a3 isoform vacuolar type H⁺-ATPase with IC50s of 170 nM, 370 nM and 220 nM for osteoclast plasma membranes, renal brush border membranes and macrophage microsomes. FR-167356 reduces bone metastasis of B16-F10 cells. |
| In vivo | In male C57BL/6 mice with B16-F10 xenografts, FR-167356 (200 mg/kg) reduces bone metastasis, inhibits tumor growth, and reduces the expression of MMP9[1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 22.5 mg/mL (59.48 mM), Sonication is recommended. |
| Keywords | Vacuolar type H+-ATPase | FR-167356 |
| Inhibitors Related | Tirofiban hydrochloride monohydrate | Sodium oleate | Omeprazole | Tolbutamide | Esomeprazole | trans-Aconitic acid | Phlorizin | Chlorpropamide | Vonoprazan Fumarate | Revaprazan hydrochloride | Oleic acid | Lansoprazole |
| Related Compound Libraries | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Inhibitor Library | Bioactive Compounds Library Max |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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