GDC-0834 Racemate NEW
| Price | $98 | $214 | $723 |
| Package | 2mg | 5mg | 50mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-12-09 |
Product Details
| Product Name: GDC-0834 Racemate | CAS No.: 1133432-46-8 |
| Supply Ability: 10g | Release date: 2025/12/09 |
Product Introduction
Bioactivity
| Name | GDC-0834 Racemate |
| Description | GDC-0834 (racemate) is the racemate form of GDC-0834, an effective and selective BTK inhibitor. |
| In vitro | GDC-0834 inhibited BTK (IC50s: 5.9 and 6.4 nM in biochemical and cellular assays) and (IC50s: 1.1 and 5.6 μM in mouse and rat) [1]. |
| In vivo | Administration of GDC-0834 (30-100 mg/kg) in a rat collagen-induced arthritis (CIA) model resulted in a dose-dependent decrease of ankle swelling and reduction of morphologic pathology [1]. GDC-0834 exhibited low clearance in PXB chimeric mice with humanized liver. GDC-0834 plasma concentrations in humans were below the limit of quantitation (<1 ng/ml) in most samples from the cohorts dosed orally at 35 and 105 mg [2]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | 10% DMSO+40% PEG300+5% Tween-80+45% Saline : 2 mg/mL (3.35 mM), Sonication is recommeded. DMSO : 49 mg/mL (82.11 mM), Sonication is recommended. |
| Keywords | GDC-0834 Racemate | GDC 0834 Racemate | GDC0834 Racemate |
| Inhibitors Related | evobrutinib | Acalabrutinib | (±)-Zanubrutinib | CP-547632 | CHMFL-EGFR-202 | Sunvozertinib | Ibrutinib | IBT6A | Orelabrutinib | Atuzabrutinib | Tyrosinase-IN-16 | Rilzabrutinib |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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| $33.00/2mg |
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2025-12-09 | |
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RongNa Biotechnology Co.,Ltd
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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