Gimatecan NEW
| Price | $35 | $81 |
| Package | 1mg | 5mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-11-04 |
Product Details
| Product Name: Gimatecan | CAS No.: 292618-32-7 |
| Purity: 98.47% | Supply Ability: 10g |
| Release date: 2025/11/04 |
Product Introduction
Bioactivity
| Name | Gimatecan |
| Description | Gimatecan (STI481) is a potent topoisomerase I inhibitor. Gimatecan is an orally bioavailable camptothecin analogue with antitumor activity. |
| In vitro | Gimatecan (3 to 300 ng/mL) significantly inhibits the growth of human bladder cancer models (HT1376 and MCR), demonstrating antiproliferative potency. At 0.003 µg/mL, Gimatecan causes a persistent S-phase arrest, with an increased number of S-phase cells observed at a higher concentration (0.03 µg/mL)[1]. |
| In vivo | Gimatecan (2 mg/kg; administered orally every fourth day for four doses) effectively inhibits tumor growth[1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 31.5 mg/mL (70.4 mM), when pH is adjusted to 10 with NaOH. Sonication and heating to 60℃ are recommended. H2O : Insoluble |
| Keywords | topoisomerase I | STI-481 | STI 481 | LBQ-707 | LBQ 707 | Gimatecan |
| Inhibitors Related | Berberine chloride | EIDD-1931 | Flumequine | Levofloxacin hydrochloride | Norfloxacin | Prulifloxacin | Enoxacin | Pefloxacin Mesylate | Ciprofloxacin | Ciprofloxacin monohydrochloride | Etoposide | Cholesteryl Hemisuccinate |
| Related Compound Libraries | Anti-Lung Cancer Compound Library | DNA Damage & Repair Compound Library | Bioactive Compound Library | Anti-Cancer Clinical Compound Library | Drug Repurposing Compound Library | Inhibitor Library | Anti-Aging Compound Library | Clinical Compound Library | Bioactive Compounds Library Max | Human Metabolite Library | Anti-Cancer Active Compound Library | Anti-Cancer Drug Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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