Gisadenafil besylate NEW
| Price | $683 | $888 | $1340 |
| Package | 25mg | 50mg | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-06-18 |
Product Details
| Product Name: Gisadenafil besylate | CAS No.: 334827-98-4 |
| Supply Ability: 10g | Release date: 2025/06/18 |
Product Introduction
Bioactivity
| Name | Gisadenafil besylate |
| Description | Gisadenafil besylate (UK 369003-26) is a potent and orally active PDE5 inhibitor (IC50=1.23 nM), 100 times more selective for PDE5 than PDE6, for the study of lower urinary tract symptoms associated with benign prostatic hyperplasia. |
| In vivo | In vivo experiments used doxycycline-inducible HIV-1 Tat transgenic mice (GFAP-driven). Gisadenafil besylate was administered intraperitoneally at 0.25 mg/kg daily for 5 days. On day 5, a 5-minute hypercapnia challenge (5% CO₂) was applied to assess cerebrovascular reactivity. The treatment significantly improved the cortical blood flow response in Tat mice from 11.6% to 17.5%, and restored dilation of small arterioles (<25 μm) to 20.6%, though gisadenafil besylate did not recover the dilation of larger vessels[1]. |
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice./Shipping at ambient temperature. |
| Solubility Information | H2O : 1 mg/mL (1.48 mM), Sonication is recommended. DMSO : 80 mg/mL (118.03 mM), Sonication is recommended. |
| Keywords | PDE5A | PDE1A | Gisadenafil besylate |
| Inhibitors Related | Theophylline monohydrate | Tadalafil | Diphylline | Acefylline | Roflumilast | Theobromine | Apremilast | Indomethacin | Icariin | Vardenafil hydrochloride | Doxofylline | Sildenafil citrate |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
You may like
Recommended supplier
| Product name | Price | Suppliers | Update time | |
|---|---|---|---|---|
| $195.00/1mg |
VIP5Y
|
TargetMol Chemicals Inc.
|
2025-06-19 | |
| $1.10/1g |
VIP5Y
|
Shaanxi Dideu Medichem Co. Ltd
|
2021-04-30 | |
| $888.00/50mg |
VIP1Y
|
TargetMol Chemicals Inc.
|
2025-06-06 |
United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
INQUIRY