Product Details
| Product Name:
GW 766994 |
CAS No.:
408303-43-5 |
| Supply Ability:
10g |
Release date:
2025/11/07 |
Product Introduction
Bioactivity
| Name | GW 766994 |
| Description | GW 766994 is a specific and oral chemokine receptor-3 (CCR3) antagonist. It has the potential for asthma and eosinophilic bronchitis treatment. |
| In vitro | GW 766994 (10 μM) counteracts CCL11-induced CDK5 activation, CDK5 and GSK3β phosphorylations, and the heightened phosphorylation of tau in hippocampal neurons. As a specific chemokine receptor-3 (CCR3) antagonist, GW 766994 has progressed to clinical trials for the treatment of asthma and eosinophilic bronchitis. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 56 mg/mL (124.07 mM), Sonication is recommended.
|
| Keywords | GW-994 | GW994 | GW-766994 | GW766994 | GW 766994 | CCR3 |
| Inhibitors Related | Aplaviroc | AZD2098 | MLN-3897 TFA | CCR2 antagonist 5 | INCB-9471 | CCR3 antagonist 1 | BMS-817399 | PF-4136309 | C-021 | Pirfenidone | Vercirnon | CCR6 antagonist 1 |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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