(-)-Phenylephrine Base

High Purity 99% CAS 59-42-7 Phenylephrine Base for Psvt in stock
Product Information
High purity 99% Cas59-42-7 Phenylephrine base for  PSVT                                                              
                                             
                                                                 Certificate of Analysis
 

Test Items	Specification	Test Results
Appearance	White or almost white crystalline powder	White crystalloid powder
Loss on drying	<=0.5%	0.24%
Optical rotation	+79°~+83°	81.4°
(HPLC)Assay	97-103.0%	98.31%
Free acid	0.5%max	0.36%
Conclusion	The aboye product conforms analysis standard

1.Specifications:
Phenylephrine hydrochloride

Synonyms: (-)-alpha-hydroxy-beta-(methylamino)ethyl-alpha-(3-hydroxybenzene)hydrochlor;1-m-hydroxy-alpha-(methylaminomethyl)benzylalcoholhydrochloride;3-hydroxy-alpha-((methylamino)methyl)-,hydrochloride,(-)-benzenemethano;almefrin;benzenemethanol,3-hydroxy-alpha-[(methylamino)methyl]-,hydrochloride,(thet;consdrin;consdrinhydrochloride;d-(-)-phenylephrinehydrochloride
CAS: 59-42-7
MF: C9H14ClNO2
MW: 203.67
EINECS: 200-424-8

Chemical Properties white to almost white crystalline powder
Usage α-Adrenergic agonist. Mydriatic; decongestant.
General Description Odorless white microcrystalline powder. Bitter taste. pH (1% aqueous solution) about 5.

Air & Water Reactions May be sensitive to prolonged exposure to air and light. Water soluble.
Reactivity Profile Phenylephrine hydrochloride is incompatible with acids, acid chlorides, acid anhydrides and oxidizing agents. Phenylephrine hydrochloride is also incompatible with butacaine, alkalis and ferric salts.
Fire Hazard Flash point data for Phenylephrine hydrochloride are not available; however, Phenylephrine hydrochloride is probably combustible.
Biological Activity α 1 -adrenoceptor agonist; pK i values are 5.86, 4.87 and 4.70 for α 1D , α 1B and α 1A receptors respectively.

2.Phenylephrine hydrochloride Applications:
Phenylephrine Hydrochloride used to produce vasoconstriction as an adjunct to correct hemodynamic imbalances in the treatment of shock that persists after adequate fluid volume replacement
Phenylephrine Hydrochloride May be ineffective if severe peripheral vasoconstriction exists and may have a deleterious effect by causing further reductions in plasma volume and blood flow to vital organs.
Phenylephrine Hydrochloride May be used to treat hypotension or shock resulting from overdosage of or idiosyncratic reactions to certain drugs
Phenylephrine Hydrochloride May be useful to control shock following pheochromocytomectomy, but shock generally can be prevented by maintenance of adequate blood volume and/or preoperative administration of an -adrenergic blocking agent

Packing&Delivery
Packing: 
  1. Inner double plastic bags----25kg/Fiber drum (35*35*45cm, GW: 28kg, NW: 25kg);
  2. Inner double plastic bags----5kg/Aluminum foil bag (GW: 6.5kg, NW: 5kg).
  3. Inner double plastic bags----1kg/Aluminum foil bag (GW: 1.5kg, NW: 1kg).
Delivery:  
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