Hydroxychloroquine Impurity NEW

Hydroxychloroquine Impurity 

Product Information

• Product Code：H002028

• English Name：Hydroxychloroquine Impurity 28

• English Alias：4,7-dichloroquinoline-3-carboxylic acid

• CAS No.：630067-21-9

• Molecular Formula：C10H5Cl2NO2

• Molecular Weight：242.06

Advantages

• High Purity Guarantee：Confirmed by HPLC (≥99.0%), NMR (1H, 13C), HRMS and other technologies, ensuring the accuracy and reliability of impurity analysis.

Research Status

• Detection Technology：UPLC-MS/MS with C18 column (1.7μm) and 0.1% formic acid-acetonitrile gradient elution achieves separation within 1.8 minutes, with LOD of 0.002 ng/mL for trace analysis.

• Formation Mechanism：Formed by reaction of furanacetic acid with methoxyamine under alkaline conditions (e.g., sodium carbonate catalysis); optimizing reaction pH (8.0-9.0) and reagent ratio inhibits side reactions.

• Safety Evaluation：In vitro antibacterial assays show MIC >64 μg/mL against Staphylococcus aureus (Cefuroxime MIC=0.5 μg/mL), with low toxicity but requiring ≤0.1% limit. Long-term stability testing is ongoing for degradation monitoring.

We can also customize related analogues and modified peptides including HPLC, MS, 1H-NMR, MS, HPLC, IR, UV, COA, MSDS.

This product is intended for laboratory use only!

WhatsAPP: +86 17320513646
E-mail: anna@molcoo.com

NEW IN STOCK!

The Molcoo Laboratory added drug impurity reference standards, including Baricitinib, Piperazine, Benzylpenicillin, Tranilast and multiple N-Nitroso drug impurities! Now available for immediate delivery!