Product Details
| Product Name:
ICI 153110 |
CAS No.:
87164-90-7 |
| Supply Ability:
10g |
Release date:
2025/08/22 |
Product Introduction
Bioactivity
| Name | ICI 153110 |
| Description | ICI 153110 is an orally active phosphodiesterase inhibitor with both inotropic and vasodilating properties, designed for the treatment of congestive cardiac failure. |
| In vivo | Administration of ICI 153110 resulted in the death of fourteen animals in both high-dose main test and reversibility groups, due to direct or indirect effects. In a female rat receiving 10 mg/kg/day of ICI 153110, a mild focal arteritis was observed, characterized by mixed cell infiltration and early fibrous tissue formation in the artery's outer layer. Premature deaths of two rats were attributed to complications from intratracheal intubation with a dosing solution at 250 mg/kg/day. Additionally, minimal focal arteritis with medial necrosis and inflammation in both the middle and outer layers of the arteries was detected in two other animals administered doses of 5 and 250 mg/kg/day. ICI 153110, an orally active compound with vasodilating and inotropic effects, is aimed at treating congestive cardiac failure. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | Phosphodiesterase | ICI-153110 | ICI153110 | ICI 153110 |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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Recommended supplier
| Product name |
Price |
|
Suppliers |
Update time |
|
|
$1520.00/25mg |
VIP4Y
|
TargetMol Chemicals Inc.
|
2025-10-27 |
United States