Indobufen Impurity 71 NEW

Product Information

Product Number: I036071

English Name: Indobufen Impurity 71

English Alias: 2-ethyl-2-(4-nitrobenzyl)malonic acid

CAS Number: 1461705-59-8

Molecular Formula: C₁₂H₁₃NO₆

Molecular Weight: 267.23

Advantages

Well-defined structure and high stability, which can be used to analyze the by-product formation mechanism of nitro substitution and alkylation reactions in indobufen synthesis, optimizing processes to control benzyl impurity generation;

As a reference standard for polar compounds containing nitro and carboxyl groups, it provides a standard substance for detecting polar impurities in drugs, improving the quantitative accuracy of methods such as HPLC;

Helps study the impact of nitro structures on drug stability and toxicological properties (nitro compounds may have potential genotoxicity) to provide a scientific basis for impurity control strategies.

Applications

Drug Development: Used as an impurity reference standard to identify and quantify Impurity 71 in indobufen preparations, evaluating the purity of APIs and formulations;

Quality Control: Acting as a standard substance to validate the sensitivity of detection methods (e.g., HPLC or LC-MS), ensuring the impurity content meets pharmacopoeia requirements during production;

Toxicological Research: Assisting in evaluating the potential genotoxicity of nitro impurities to provide dat