JNJ-1289 NEW
| Price | $83 | $217 | $306 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-12-09 |
Product Details
| Product Name: JNJ-1289 | CAS No.: 792898-18-1 |
| Purity: 98.16% | Supply Ability: 10g |
| Release date: 2025/12/09 |
Product Introduction
Bioactivity
| Name | JNJ-1289 |
| Description | JNJ-1289 is a selective, potent, and competitive inhibitor of human spermine oxidase (hSMOX) with an IC50 value of 50 nM.JNJ-1289 has potential anticancer and anti-inflammatory activity for the study of polyamine catabolic disorders. |
| In vitro | In a time-dependent manner, JNJ-1289 inhibits hSMOX activity, with assessments at 0 and 2 hours[1]. Initially, JNJ-1289 forms a weak complex with hSMOX, characterized by an apparent Ki value of 1.4 μM. Subsequently, a relatively slow protein isomerization occurs, leading to the formation of the final tightly bound inhibitor-enzyme complex[1]. |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | 10% DMSO+90% Saline : 2.5 mg/mL (8.11 mM), Sonication is recommeded. DMSO : 50 mg/mL (162.15 mM), Sonication is recommended. |
| Keywords | hSmo |
| Inhibitors Related | IHR-1 | ALLO-2 | Purmorphamine | LEQ506 | Halcinonide | MRT-83 | BMS-833923 | SAG | Sonidegib | SMO-IN-2 | Jervine | MK-4101 |
| Related Compound Libraries | Bioactive Compound Library | Inhibitor Library | Stem Cell Differentiation Compound Library | Anti-Aging Compound Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library | Wnt/Hedgehog/Notch Compound Library | Anti-Cancer Active Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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United States