Lactisole NEW
| Price | $29 |
| Package | 500mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-12-02 |
Product Details
| Product Name: Lactisole | CAS No.: 150436-68-3 |
| Purity: 98.96% | Supply Ability: 10g |
| Release date: 2025/12/02 |
Product Introduction
Bioactivity
| Name | Lactisole |
| Description | Lactisole (na-PMP) is an inhibitor of the glucose-sensing receptor |
| In vitro | In MIN6 cells, in a dose-dependent manner, lactisole inhibited insulin secretion induced by sweeteners, acesulfame-K, sucralose and glycyrrhizin. The IC50 was ～4 mmol/l. Lactisole attenuated the elevation of cytoplasmic Ca2+ concentration ([Ca2+]c) evoked by sucralose and acesulfame-K but did not affect the elevation of intracellular cAMP concentration ([cAMP]c) induced by these sweeteners. Lactisole also inhibited the action of glucose in MIN6 cells. Thus, lactisole significantly reduced elevations of intracellular [NADH] and intracellular [ATP] induced by glucose, and also inhibited glucose-induced insulin secretion[1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | Ethanol : 1 mg/mL (4.58 mM), Sonication is recommended. DMSO : 45 mg/mL (206.25 mM), Sonication is recommended. DMF : 20 mg/mL (91.67 mM), Sonication is recommended. 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (9.17 mM), Sonication is recommended. |
| Keywords | Tastereceptor | Taste receptor | Sweet taste receptor | Lactisole |
| Inhibitors Related | Aspartame |
| Related Compound Libraries | Bioactive Compound Library | ReFRAME Related Library | Food Additive Library | Drug Repurposing Compound Library | Inhibitor Library | Metabolism Compound Library | Clinical Compound Library | Bioactive Compounds Library Max |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
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