Lqvtdsglyrcviyhpp TFA NEW
| Price | $60 | $147 |
| Package | 1mg | 5mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-04-30 |
Product Details
| Product Name: Lqvtdsglyrcviyhpp TFA | Purity: 95% |
| Supply Ability: 10g | Release date: 2025/04/30 |
Product Introduction
Bioactivity
| Name | Lqvtdsglyrcviyhpp TFA |
| Description | LQVTDSGLYRCVIYHPP (LP17) TFA is a TREM-1 (triggering receptor expressed on myeloid cells) inhibitory peptide that significantly reduces ischemic infarction and neuronal damage, with the ability to penetrate the brain to inhibit TREM-1 [1]. |
| In vitro | METHODS: LQVTDSGLYRCVIYHPP (LP17) TFA (1 or 10 μM) was used in microglia to investigate the function of TREM-1 in the microglial OGD model by real-time quantitative PCR. RESULTS: LQVTDSGLYRCVIYHPP (LP17) TFA significantly reduced the mRNA levels of proinflammatory cytokines (NLRP3, IL-1β, IL-18, IL-6, CD16, CD32, and iNOS) and chemokines (MCP-1, CXCL-1, and CXCL-2); microglia incubated with LQVTDSGLYRCVIYHPP (LP17) maximally preserved neuronal viability. [1] |
| In vivo | METHODS: LQVTDSGLYRCVIYHPP (LP17) TFA (1 mg/kg, intranasal) was used to confirm the biological function of TREM-1 in ischemic stroke. RESULTS: LQVTDSGLYRCVIYHPP (LP17) TFA induced a significant decrease in TUNEL-positive cells and FJC-positive neurons. [1] |
| Storage | keep away from moisture,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | H2O : < 1 mg/mL (insoluble) DMSO : 80 mg/mL (38.55 mM), Sonication is recommended. |
| Keywords | TREM1 |
| Related Compound Libraries | Peptide Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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