Product Details
| Product Name:
LY3372689 |
CAS No.:
2241514-56-5 |
| Purity:
99.53% |
Supply Ability:
10g |
| Release date:
2025/12/04 |
Product Introduction
Bioactivity
| Name | LY3372689 |
| Description | LY3372689 (Formulaic Ia) is an orally active O-GlcNAcase (OGA) enzyme inhibitor targeting tau protein-based disorders, including Alzheimer's disease. |
| In vivo | In rat studies, LY3372689 demonstrated a dose-dependent change in OGA EO following a single oral dose with a maximum EO of greater than 90%. A plasma concentration-dependent increase in brain OGA EO was observed with EO exceeding 90% at 24 hours following the highest dose of LY3372689 administered.[1] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 225 mg/mL (586.79 mM), Sonication is recommended.
|
| Keywords | tau | O-GlcNAcase | MicrotubuleAssociated | Microtubule Associated | LY-3372689 | LY3372689 | LY 3372689 |
| Inhibitors Related | Flubendazole | N-Phenylbenzylamine | Mebendazole | 4-Isopropoxybenzoic acid | Oxfendazole | Thiabendazole | Methylene Blue | Methylene Blue trihydrate | Griseofulvin | Paclitaxel | 4'-Demethylepipodophyllotoxin | Albendazole |
| Related Compound Libraries | Bioactive Compound Library | Anti-Alzheimer's Disease Compound Library | Drug Repurposing Compound Library | Microtubule-Targeted Compound Library | Inhibitor Library | Orally Active Compound Library | Clinical Compound Library | Bioactive Compounds Library Max | Fluorochemical Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
| Product name |
Price |
|
Suppliers |
Update time |
|
|
$/ |
|
Anhui Ruihan Technology Co., Ltd
|
2023-08-21 |
United States