Product Details
| Product Name:
MAZ51 |
CAS No.:
163655-37-6 |
| Purity:
98.53% |
Supply Ability:
10g |
| Release date:
2025/09/18 |
Product Introduction
Bioactivity
| Name | MAZ51 |
| Description | MAZ51 is a VEGFR-3 (Flt-4) tyrosine kinase inhibitor. |
| In vitro | MAZ51 is able to block the proliferation of VEGFR-3-expressing human endothelial cells and is less potently able to induce their apoptosis.?MAZ51 also inhibits the proliferation and induces the apoptosis of a variety of non-VEGFR-3-expressing tumor cell lines[1]. |
| In vivo | In vivo, MAZ51 significantly inhibits the growth of rat mammary carcinomas.?These data establish MAZ51 as a compound with antitumor properties that inhibits tumor growth directly and also indirectly by interfering with tumor-host interactions[1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 3.33 mg/mL (10.59 mM), Sonication is recommended.
|
| Keywords | VEGFR3 | VEGFR | VEGF-D | VEGF-C | Vascular endothelial growth factor receptor | tumor | proliferation | phosphorylation | PDGFRβ | MAZ-51 | MAZ51 | MAZ 51 | ligand-induced | Inhibitor | inhibit | indolinone | IGF-1R | growth | EGFR | Apoptosis |
| Inhibitors Related | Stavudine | 5-Fluorouracil | Flubendazole | Cysteamine hydrochloride | Myricetin | Sodium 4-phenylbutyrate | L-Ascorbic acid | L-Glutamic acid | Tributyrin | L-Ascorbic acid sodium salt | Alginic acid | Dextran sulfate sodium salt (MW 5000) |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
| Product name |
Price |
|
Suppliers |
Update time |
|
|
$/ |
|
Anhui Ruihan Technology Co., Ltd
|
2023-08-21 |
United States