Mc-Val-Cit-PAB-Cl NEW
| Price | $97 | $245 | $395 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-10-10 |
Product Details
| Product Name: Mc-Val-Cit-PAB-Cl | CAS No.: 1639351-92-0 |
| Purity: 99.79% | Supply Ability: 10g |
| Release date: 2025/10/10 |
Product Introduction
Bioactivity
| Name | Mc-Val-Cit-PAB-Cl |
| Description | Mc-Val-Cit-PAB-Cl, a cleavable ADC linker, is utilized in the conjugation of MMAE and antibodies to produce compounds such as antibody-MC-vc-MMAE (e.g., anti-CD22-MC-VC-PABC-MMAE), which demonstrate cytotoxicity with IC50s of 3.3 and 0.95 nM against BJAB and WSU cell lines, respectively. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | Mc-Val-Cit-PAB-Cl | McValCitPABCl | Mc Val Cit PAB Cl | Inhibitor | inhibit | Cleavable | Antibody-drug conjugates linkers | ADCLinker | ADC Linkers | ADC Linker |
| Inhibitors Related | N-Boc-PEG5-bromide | Boc-C16-COOH | Succinic anhydride | DSS Crosslinker | Val-cit-PAB-OH | Fmoc-8-amino-3,6-dioxaoctanoic acid | Fmoc-Gly-Gly-OH | SMCC | Boc-NH-PEG4-CH2COOH | EMCS | DSP Crosslinker | DSG Crosslinker |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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United States