Product Details
| Product Name:
Medroxalol |
CAS No.:
56290-94-9 |
| Supply Ability:
10g |
Release date:
2025/10/27 |
Product Introduction
Bioactivity
| Name | Medroxalol |
| Description | Medroxalol (RMI81968) is an orally active adrenergic receptor antagonist that blocks both α- and β-adrenergic receptors, producing antihypertensive and vasodilating effects [1]. |
| In vitro | Medroxalol, at concentrations ranging from 0.1-10 μM over a 20-minute incubation period, exhibits antagonistic activity against both α- and β-adrenergic receptors in isolated rabbit aortic strips, as demonstrated by the Cell Viability Assay. Specifically, the assay results reveal pA2 values of 6.09 for α-adrenergic receptors and 7.73 for β-adrenergic receptors, indicating its efficacy in blocking these receptor types [1]. |
| In vivo | Medroxalol treatment, administered via oral gavage at dosages of 12.5 to 50 mg/kg once daily for 12 days, demonstrates antihypertensive activity by inducing a dose-dependent decrease in blood pressure in male spontaneously hypertensive rats (SHR) [1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Inhibitors Related | Trifluoperazine dihydrochloride | Olanzapine | Mirtazapine | Octopamine hydrochloride | Gemfibrozil | Buflomedil hydrochloride | Dexmedetomidine hydrochloride | Isoprenaline hydrochloride | Propranolol hydrochloride | Trazodone hydrochloride | Mianserin hydrochloride | Atenolol |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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Recommended supplier
| Product name |
Price |
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Suppliers |
Update time |
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$/ |
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Anhui Ruihan Technology Co., Ltd
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2023-08-21 |
United States