ML-148 NEW
| Price | $55 | $168 | $267 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-12-05 |
Product Details
| Product Name: ML-148 | CAS No.: 451496-96-1 |
| Purity: 99.88% | Supply Ability: 10g |
| Release date: 2025/12/05 |
Product Introduction
Bioactivity
| Name | ML-148 |
| Description | ML-148 is a selective inhibitor of 15-hydroxy prostaglandin dehydrogenase (15-PGDH, IC50 = 56 nM). ML-148 can be used to profile across a panel of related dehydrogenase or reductase enzymes and in studies about prostaglandin-signaling pathways. |
| In vitro | ML148 (10 nM) reduces the apparent Km by half and decreases Vmax by 25%. ML148 shows selectivity with IC50s of 36000, >57500, >57500 nM for ALDH1A1, HADH2, HSD17β4, respectively[1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMF:PBS(pH 7.2)(1:1) : 0.5 mg/mL (1.57 mM), Sonication is recommended. DMSO : 11 mg/mL (34.44 mM), Sonication is recommended. DMF : 25 mg/mL (78.27 mM), Sonication is recommended. Ethanol : 10 mg/mL (31.31 mM), Sonication is recommended. |
| Keywords | selective | prostaglandin-signaling | PGE2 | NAD+ | ML-148 | ML148 | ML 148 | Inhibitor | inhibit | 15-PGDH | 15-Hydroxyprostaglandin dehydrogenase |
| Inhibitors Related | Disulfiram | Methotrexate | Rotenone | Mycophenolate Mofetil | Ribavirin | Mycophenolic acid | 4-Diethylaminobenzaldehyde | Benzyl alcohol | Isomalt | Isoniazid | D-Mannitol | Ivosidenib |
| Related Compound Libraries | Bioactive Compound Library | Anti-Cancer Metabolism Compound Library | Inhibitor Library | Metabolism Compound Library | Bioactive Compounds Library Max |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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