ML-210 NEW
| Price | $30 | $44 | $79 |
| Package | 1mg | 2mg | 5mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-12-05 |
Product Details
| Product Name: ML-210 | CAS No.: 1360705-96-9 |
| Purity: 99.03% | Supply Ability: 10g |
| Release date: 2025/12/05 |
Product Introduction
Bioactivity
| Name | ML-210 |
| Description | ML-210 (CID 49766530) is a glutathione peroxidase 4 (GPX4) inhibitor (EC50=30 nM) that is covalent and selective. ML-210 has antitumor activity and induces ferroptosis. |
| In vitro | METHODS: Human lung adenocarcinoma cell line HCC4006 was treated with ML-210 (10 µM) for 1 h. CETSA profiles were detected by Western Blot. RESULTS: ML-210 affects the thermal stability of GPX4, consistent with the binding to the cellular target. [1] METHODS: DRD cell lines were treated with ML-210 for 48 h, and cell viability was measured. RESULTS: ML-210 has an IC50 of 107 nM in the DRD cell line. [2] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 11 mg/mL (23.14 mM), Sonication is recommended. 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 1.1 mg/mL (2.31 mM), Suspension. |
| Keywords | selenocysteine | residue | Ras | peroxidase | ML-210 | ML210 | ML 210 | Inhibitor | inhibit | Gpx4 | GPX4 | GlutathionePeroxidase | Glutathione Peroxidase | glutathione | Ferroptosis | Covalent | CID-49766530 | CID49766530 | anti-cancer |
| Inhibitors Related | Rosiglitazone | Acetylcysteine | Deferiprone | L-Glutamic acid | Sorafenib | 4-Aminosalicylic acid | Curcumin | Gallic Acid Monohydrate | L-Cystine | L-Glutamine | (-)-Epigallocatechin Gallate | Coenzyme Q10 |
| Related Compound Libraries | Apoptosis Compound Library | Reprogramming Compound Library | Pain-Related Compound Library | Bioactive Compound Library | Membrane Protein-targeted Compound Library | HIF-1 Signaling Pathway Compound Library | Inhibitor Library | Immunology/Inflammation Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | GPCR Compound Library | Anti-Cancer Active Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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