NBDHEX NEW
| Price | $30 | $64 | $98 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-12-05 |
Product Details
| Product Name: NBDHEX | CAS No.: 787634-60-0 |
| Purity: 97.38% | Supply Ability: 10g |
| Release date: 2025/12/05 |
Product Introduction
Bioactivity
| Name | NBDHEX |
| Description | NBDHEX is a potent inhibitor of glutathione S-transferase P1-1 (GSTP1-1). |
| In vitro | NBDHEX not only is cytotoxic toward the parental small cell lung cancer H69 cell line (LC(50) of 2.3 +/- 0.6 micromol/L) but also overcomes the multidrug resistance of its variant, H69AR, which overexpresses the ATP-binding cassette transporter multidrug resistance-associated protein 1 (MRP1;?LC(50) of 4.5 +/- 0.9 micromol/L).?Drug efflux experiments, done in the presence of a specific inhibitor of MRP1, confirmed that NBDHEX is not a substrate for this export pump [1]. |
| In vivo | NBDHEX, In female mice, treatment results in a statistically significant tumour inhibition (approximately 70%) [1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 125 mg/mL (420.41 mM), Sonication is recommended. 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 4 mg/mL (13.45 mM), Sonication is recommended. |
| Keywords | p38MAPK | NBDHEX | JNK | Inhibitor | inhibit | GSTP1-1 | GSSG | GlutathionePeroxidase | Glutathione Peroxidase | extrusion | cytotoxic | c-Jun | catalytic | Autophagy | Apoptosis | anticancer |
| Inhibitors Related | Stavudine | Aceglutamide | Cysteamine hydrochloride | Hydroxychloroquine | Metronidazole | Guanidine hydrochloride | Citric Acid Triammonium | Tributyrin | Paeonol | Naringin | Alginic acid | Dextran sulfate sodium salt (MW 5000) |
| Related Compound Libraries | Apoptosis Compound Library | Bioactive Compound Library | Glutamine Metabolism Compound Library | Autophagy Compound Library | Inhibitor Library | NO PAINS Compound Library | Metabolism Compound Library | PPI Inhibitor Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library | Anti-Cancer Active Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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| Product name | Price | Suppliers | Update time | |
|---|---|---|---|---|
| $30.00/1mg |
VIP4Y
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TargetMol Chemicals Inc.
|
2025-12-05 |
United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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