Noladin ether NEW
| Price | $133 | $548 | $983 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-12-03 |
Product Details
| Product Name: Noladin ether | CAS No.: 222723-55-9 |
| Supply Ability: 10g | Release date: 2025/12/03 |
Product Introduction
Bioactivity
| Name | Noladin ether |
| Description | Noladin ether (2-AG ether) is a selective and potent cannabinoid CB1 receptor agonist, reducing sensory nerve transmission in rat mesenteric artery beds through a non-CB1/CB2 G(i/o) receptor pathway in a concentration-dependent manner. |
| In vitro | In the porcine anterior segment perfusion organ culture model, Noladin ether (3, 30, 300 nM) treatment resulted in a dependent increase in the concentration of aqueous outflow facilities. Treatment of trabecular reticulum cells with Noladin ether (30 nM) can activate p42/44 MAP kinase, and cause the trabecular reticulum cells to become round, actin stress fibers to decrease, and adhesion plaques to decrease. [1] |
| In vivo | Intraperitoneal injection of Noladin ether (0.5, 1.0, and 2.0 mg/kg) in male rats increased food intake dose-dependently by affecting CB (1) receptors. [2] |
| Storage | keep away from direct sunlight,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | Ethanol:PBS(pH 7.2) (1:1) : 500 μg/mL, Sonication is recommended. PBS (pH 7.2) : < 1 mg/mL (insoluble) DMF : 8 mg/mL (21.94 mM), Sonication is recommended. DMSO : 8 mg/mL (21.94 mM), Sonication is recommended. Ethanol : < 1 mg/mL (insoluble) |
| Keywords | Noladin ether |
| Inhibitors Related | RTICBM-189 | β-Caryophyllene | CB2 modulator 1 | Pregnenolone | Pregnenolone acetate | CB1 antagonist 2 | Dehydroabiethylamine | CB2 receptor agonist 2 | AM-1235 | 2,3-Butanediol | Drinabant | AM281 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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